Oculopharyngeal muscular dystrophy as a cause of progression of weakness in antibody positive myasthenia gravis

Bjorn Oskarsson, Steven P. Ringel

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Many neuromuscular conditions cause bulbar and limb weakness, and when several conditions coexist they present additional diagnostic challenges. Here we describe a case of a 45-year-old woman with antibody positive myasthenia gravis since age 16, who then develops treatment-resistant weakness due to genetically proven oculopharyngeal muscular dystrophy. We conclude that the development of treatment-resistant weakness in myasthenia gravis should spur further work up for other neuromuscular disorders including oculopharyngeal muscular dystrophy.

Original languageEnglish (US)
Pages (from-to)316-318
Number of pages3
JournalNeuromuscular Disorders
Volume23
Issue number4
DOIs
StatePublished - Apr 1 2013
Externally publishedYes

Fingerprint

Oculopharyngeal Muscular Dystrophy
Myasthenia Gravis
Antibodies
Extremities
Therapeutics

Keywords

  • Myasthenia gravis (MG)
  • Oculopharyngeal muscular dystrophy (OPMD)

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Genetics(clinical)
  • Neurology

Cite this

Oculopharyngeal muscular dystrophy as a cause of progression of weakness in antibody positive myasthenia gravis. / Oskarsson, Bjorn; Ringel, Steven P.

In: Neuromuscular Disorders, Vol. 23, No. 4, 01.04.2013, p. 316-318.

Research output: Contribution to journalArticle

@article{d3a1dbcffd6e47ca94acda6d58b50d76,
title = "Oculopharyngeal muscular dystrophy as a cause of progression of weakness in antibody positive myasthenia gravis",
abstract = "Many neuromuscular conditions cause bulbar and limb weakness, and when several conditions coexist they present additional diagnostic challenges. Here we describe a case of a 45-year-old woman with antibody positive myasthenia gravis since age 16, who then develops treatment-resistant weakness due to genetically proven oculopharyngeal muscular dystrophy. We conclude that the development of treatment-resistant weakness in myasthenia gravis should spur further work up for other neuromuscular disorders including oculopharyngeal muscular dystrophy.",
keywords = "Myasthenia gravis (MG), Oculopharyngeal muscular dystrophy (OPMD)",
author = "Bjorn Oskarsson and Ringel, {Steven P.}",
year = "2013",
month = "4",
day = "1",
doi = "10.1016/j.nmd.2013.01.012",
language = "English (US)",
volume = "23",
pages = "316--318",
journal = "Neuromuscular Disorders",
issn = "0960-8966",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - Oculopharyngeal muscular dystrophy as a cause of progression of weakness in antibody positive myasthenia gravis

AU - Oskarsson, Bjorn

AU - Ringel, Steven P.

PY - 2013/4/1

Y1 - 2013/4/1

N2 - Many neuromuscular conditions cause bulbar and limb weakness, and when several conditions coexist they present additional diagnostic challenges. Here we describe a case of a 45-year-old woman with antibody positive myasthenia gravis since age 16, who then develops treatment-resistant weakness due to genetically proven oculopharyngeal muscular dystrophy. We conclude that the development of treatment-resistant weakness in myasthenia gravis should spur further work up for other neuromuscular disorders including oculopharyngeal muscular dystrophy.

AB - Many neuromuscular conditions cause bulbar and limb weakness, and when several conditions coexist they present additional diagnostic challenges. Here we describe a case of a 45-year-old woman with antibody positive myasthenia gravis since age 16, who then develops treatment-resistant weakness due to genetically proven oculopharyngeal muscular dystrophy. We conclude that the development of treatment-resistant weakness in myasthenia gravis should spur further work up for other neuromuscular disorders including oculopharyngeal muscular dystrophy.

KW - Myasthenia gravis (MG)

KW - Oculopharyngeal muscular dystrophy (OPMD)

UR - http://www.scopus.com/inward/record.url?scp=84874999329&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874999329&partnerID=8YFLogxK

U2 - 10.1016/j.nmd.2013.01.012

DO - 10.1016/j.nmd.2013.01.012

M3 - Article

C2 - 23453859

AN - SCOPUS:84874999329

VL - 23

SP - 316

EP - 318

JO - Neuromuscular Disorders

JF - Neuromuscular Disorders

SN - 0960-8966

IS - 4

ER -