Occupation-related squatting, kneeling, and heavy lifting and the knee joint

A magnetic resonance imaging-based study in men

Shreyasee Amin, Joyce Goggins, Jingbo Niu, Ali Guermazi, Mikayel Grigoryan, David J. Hunter, Harry K. Genant, David T. Felson

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Objective. We examined the relation between occupational exposures to frequent squatting/kneeling and/or heavy lifting with cartilage morphology, based on magnetic resonance imaging (MRI), at the tibiofemoral and patellofemoral joints in men and determined which compartments are most affected. Methods. We evaluated 192 men with symptomatic knee osteoarthritis (OA). The more symptomatic knee was imaged using MRI. Cartilage was scored using the Whole Organ MRI Score semiquantitative method at the medial and lateral tibiofemoral joint and patellofemoral joint. Occupational exposures to frequent squatting, kneeling, and/or heavy lifting were assessed using a validated questionnaire. Results. Among the 192 men [mean (± standard deviation) age 69 ± 9 yrs, body mass index (BMI) 30.8 ± 4.7 kg/m 2], those reporting occupational exposure to squatting/kneeling alone, heavy lifting alone, both squatting/kneeling and heavy lifting, or none of these activities numbered 7, 40, 47, and 98, respectively. Compared with men with no occupational exposure to these activities, and following adjustment for age, BMI, and history of knee injury or surgery, we found that men reporting occupational exposures to both squatting/kneeling and heavy lifting had a modest increased risk for worse cartilage morphology scores at the patellofemoral joint [odds ratio (OR) 1.8, 95% confidence interval (CI) 1.1 to 3.2] and medial tibiofemoral joint (OR 1.6, 95% CI 0.9, 3.0), although the latter did not reach statistical significance. Conclusion. Men with frequent occupational squatting/kneeling and heavy lifting have a greater likelihood for worse cartilage morphology scores at the patellofemoral joint. These findings add support to the important role of biomechanical loading on the pathogenesis of knee OA, particularly patellofemoral OA.

Original languageEnglish (US)
Pages (from-to)1645-1649
Number of pages5
JournalJournal of Rheumatology
Volume35
Issue number8
StatePublished - Aug 2008

Fingerprint

Knee Joint
Occupations
Patellofemoral Joint
Occupational Exposure
Magnetic Resonance Imaging
Cartilage
Knee Osteoarthritis
Body Mass Index
Joints
Odds Ratio
Confidence Intervals
Knee Injuries
Osteoarthritis
Knee

Keywords

  • Cartilage
  • Knee osteoarthritis
  • Magnetic resonance imaging
  • Occupational diseases
  • Patella

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Amin, S., Goggins, J., Niu, J., Guermazi, A., Grigoryan, M., Hunter, D. J., ... Felson, D. T. (2008). Occupation-related squatting, kneeling, and heavy lifting and the knee joint: A magnetic resonance imaging-based study in men. Journal of Rheumatology, 35(8), 1645-1649.

Occupation-related squatting, kneeling, and heavy lifting and the knee joint : A magnetic resonance imaging-based study in men. / Amin, Shreyasee; Goggins, Joyce; Niu, Jingbo; Guermazi, Ali; Grigoryan, Mikayel; Hunter, David J.; Genant, Harry K.; Felson, David T.

In: Journal of Rheumatology, Vol. 35, No. 8, 08.2008, p. 1645-1649.

Research output: Contribution to journalArticle

Amin, S, Goggins, J, Niu, J, Guermazi, A, Grigoryan, M, Hunter, DJ, Genant, HK & Felson, DT 2008, 'Occupation-related squatting, kneeling, and heavy lifting and the knee joint: A magnetic resonance imaging-based study in men', Journal of Rheumatology, vol. 35, no. 8, pp. 1645-1649.
Amin, Shreyasee ; Goggins, Joyce ; Niu, Jingbo ; Guermazi, Ali ; Grigoryan, Mikayel ; Hunter, David J. ; Genant, Harry K. ; Felson, David T. / Occupation-related squatting, kneeling, and heavy lifting and the knee joint : A magnetic resonance imaging-based study in men. In: Journal of Rheumatology. 2008 ; Vol. 35, No. 8. pp. 1645-1649.
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abstract = "Objective. We examined the relation between occupational exposures to frequent squatting/kneeling and/or heavy lifting with cartilage morphology, based on magnetic resonance imaging (MRI), at the tibiofemoral and patellofemoral joints in men and determined which compartments are most affected. Methods. We evaluated 192 men with symptomatic knee osteoarthritis (OA). The more symptomatic knee was imaged using MRI. Cartilage was scored using the Whole Organ MRI Score semiquantitative method at the medial and lateral tibiofemoral joint and patellofemoral joint. Occupational exposures to frequent squatting, kneeling, and/or heavy lifting were assessed using a validated questionnaire. Results. Among the 192 men [mean (± standard deviation) age 69 ± 9 yrs, body mass index (BMI) 30.8 ± 4.7 kg/m 2], those reporting occupational exposure to squatting/kneeling alone, heavy lifting alone, both squatting/kneeling and heavy lifting, or none of these activities numbered 7, 40, 47, and 98, respectively. Compared with men with no occupational exposure to these activities, and following adjustment for age, BMI, and history of knee injury or surgery, we found that men reporting occupational exposures to both squatting/kneeling and heavy lifting had a modest increased risk for worse cartilage morphology scores at the patellofemoral joint [odds ratio (OR) 1.8, 95{\%} confidence interval (CI) 1.1 to 3.2] and medial tibiofemoral joint (OR 1.6, 95{\%} CI 0.9, 3.0), although the latter did not reach statistical significance. Conclusion. Men with frequent occupational squatting/kneeling and heavy lifting have a greater likelihood for worse cartilage morphology scores at the patellofemoral joint. These findings add support to the important role of biomechanical loading on the pathogenesis of knee OA, particularly patellofemoral OA.",
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AU - Guermazi, Ali

AU - Grigoryan, Mikayel

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AU - Genant, Harry K.

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