Nuts and Bolts of Patient-Reported Outcomes in Orthopaedics

Minji K. Lee; Isabella Zaniletti; Dirk R. Larson; David G. Lewallen; Daniel J. Berry; Hilal Maradit Kremers

doi:10.1016/j.arth.2022.11.011

Nuts and Bolts of Patient-Reported Outcomes in Orthopaedics

Minji K. Lee, Isabella Zaniletti, Dirk R. Larson, David G. Lewallen, Daniel J. Berry, Hilal Maradit Kremers

Quantitative Health Sciences

Research output: Contribution to journal › Review article › peer-review

Abstract

Patient-reported outcomes (PROs) are commonly used in orthopaedic clinical practice, comparative effectiveness research (CER), and label claims. In this paper, we provide an overview of PROs, their development, validation, and use in orthopaedic research with examples and conclude with practical guidelines for researchers and reviewers. We discuss considerations for conceptual framework, validity, reliability, factor analysis, and measurement of change with Knee Injury and Osteoarthritis Outcome score (KOOS), as an example. We also describe advantages of instruments developed based on item response theory and statistical analyses for data collected using PRO measures. Please visit the following (https://www.youtube.com/watch?v=4p-DtZgUHOA&t=354s) for a video that explains the highlights of the paper in practical terms.

Original language	English (US)
Pages (from-to)	616-621
Number of pages	6
Journal	Journal of Arthroplasty
Volume	38
Issue number	4
DOIs	https://doi.org/10.1016/j.arth.2022.11.011
State	Published - Apr 2023

Keywords

factor analysis
function
pain
patient reported outcomes
quality of life
total joint arthroplasty

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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10.1016/j.arth.2022.11.011

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abstract = "Patient-reported outcomes (PROs) are commonly used in orthopaedic clinical practice, comparative effectiveness research (CER), and label claims. In this paper, we provide an overview of PROs, their development, validation, and use in orthopaedic research with examples and conclude with practical guidelines for researchers and reviewers. We discuss considerations for conceptual framework, validity, reliability, factor analysis, and measurement of change with Knee Injury and Osteoarthritis Outcome score (KOOS), as an example. We also describe advantages of instruments developed based on item response theory and statistical analyses for data collected using PRO measures. Please visit the following (https://www.youtube.com/watch?v=4p-DtZgUHOA&t=354s) for a video that explains the highlights of the paper in practical terms.",

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AU - Berry, Daniel J.

AU - Maradit Kremers, Hilal

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Nuts and Bolts of Patient-Reported Outcomes in Orthopaedics

Abstract

Keywords

ASJC Scopus subject areas

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