Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Case Reports and Review of the Literature

Kenneth S. Zurcher, Odette M. Houghton, Joanne F. Shen, Mahesh Seetharam, Michael C. Roarke, Ming Yang

Research output: Contribution to journalArticlepeer-review

Abstract

Ocular melanoma (OM) is a rare noncutaneous malignancy and consists of 2 different subtypes based on the anatomic location in the eye: uveal melanoma and conjunctival melanoma. Like cutaneous melanoma, OM benefits from nuclear medicine and molecular imaging in nodal staging and clinical management. Through the illustration of 2 distinctive cases, we aim to demonstrate the complementary roles of standard lymphoscintigraphy, advanced SPECT/CT, 18F-FDG PET/CT, and 18F-FDG PET/MRI in accurate nodal staging and surveillance of OM. We also review the epidemiology, existing staging guidelines, and management of uveal melanoma and conjunctival melanoma.

Original languageEnglish (US)
Pages (from-to)275-280
Number of pages6
JournalJournal of nuclear medicine technology
Volume49
Issue number3
DOIs
StatePublished - Sep 1 2021

Keywords

  • 18F-FDG/PET
  • SPECT
  • conjunctival melanoma
  • lymphoscintigraphy
  • uveal melanoma

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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