TY - JOUR
T1 - Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study
AU - Schneider, Andrea L.C.
AU - Sharrett, Albert Richey
AU - Gottesman, Rebecca F.
AU - Coresh, Josef
AU - Coker, Laura
AU - Wruck, Lisa
AU - Selnes, Ola A.
AU - Deal, Jennifer
AU - Knopman, David
AU - Mosley, Thomas H.
N1 - Publisher Copyright:
© 2014 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2015/3/6
Y1 - 2015/3/6
N2 - Accurate assessment of cognitive impairment requires comparison of cognitive performance in individuals to performance in a comparable healthy normative population. Few prior studies have included a large number of black participants and few have excluded participants from the normative sample with subclinical/latent neurological disease or dementia. This study provides age, race, and education-specific normative data for 8 cognitive tests derived from 320 black and 392 white participants aged 61 to 82 years (mean 71 y) in the Atherosclerosis Risk in Communities (ARIC) study without clinical or subclinical/latent neurological disease. Normative data are provided for the Delayed Word Recall Test, Logical Memory Parts I and II, the Word Fluency Test, Animal Naming, the Trail Making Test Parts A and B and the Digit Symbol Substitution Test. Age, race, and education-specific mean and 1.5 SD scores are given in tabular form and graphically, as well as regression-based equations to derive adjusted score cut-points. These robust normative data should enhance comparison across studies of cognitive aging, where these measures are widely used, and improve interpretation of performance on these tests for the diagnosis of cognitive impairment not only within the ARIC cohort, but also among older blacks and whites with similar demographics.
AB - Accurate assessment of cognitive impairment requires comparison of cognitive performance in individuals to performance in a comparable healthy normative population. Few prior studies have included a large number of black participants and few have excluded participants from the normative sample with subclinical/latent neurological disease or dementia. This study provides age, race, and education-specific normative data for 8 cognitive tests derived from 320 black and 392 white participants aged 61 to 82 years (mean 71 y) in the Atherosclerosis Risk in Communities (ARIC) study without clinical or subclinical/latent neurological disease. Normative data are provided for the Delayed Word Recall Test, Logical Memory Parts I and II, the Word Fluency Test, Animal Naming, the Trail Making Test Parts A and B and the Digit Symbol Substitution Test. Age, race, and education-specific mean and 1.5 SD scores are given in tabular form and graphically, as well as regression-based equations to derive adjusted score cut-points. These robust normative data should enhance comparison across studies of cognitive aging, where these measures are widely used, and improve interpretation of performance on these tests for the diagnosis of cognitive impairment not only within the ARIC cohort, but also among older blacks and whites with similar demographics.
KW - ARIC Study
KW - cognitive performance
KW - neuropsychological testing
KW - normative data
KW - race
UR - http://www.scopus.com/inward/record.url?scp=84924241560&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84924241560&partnerID=8YFLogxK
U2 - 10.1097/WAD.0000000000000042
DO - 10.1097/WAD.0000000000000042
M3 - Article
C2 - 24759546
AN - SCOPUS:84924241560
SN - 0893-0341
VL - 29
SP - 32
EP - 44
JO - Alzheimer disease and associated disorders
JF - Alzheimer disease and associated disorders
IS - 1
ER -