Non-conventional dysplasias of the tubular gut: a review and illustration of their histomorphological spectrum

Daniela Pereira; Bence Kővári; Ian Brown; Paula Chaves; Won Tak Choi; Till Clauditz; Masoumeh Ghayouri; Kun Jiang; Gregory C. Miller; Yukihiro Nakanishi; Kyoung M. Kim; Baek H. Kim; Marian P. Kumarasinghe; Ryoji Kushima; Tetsuo Ushiku; Masato Yozu; Amitabh Srivastava; John R. Goldblum; Rish K. Pai; Gregory Y. Lauwers

doi:10.1111/his.14294

Non-conventional dysplasias of the tubular gut: a review and illustration of their histomorphological spectrum

Daniela Pereira, Bence Kővári, Ian Brown, Paula Chaves, Won Tak Choi, Till Clauditz, Masoumeh Ghayouri, Kun Jiang, Gregory C. Miller, Yukihiro Nakanishi, Kyoung M. Kim, Baek H. Kim, Marian P. Kumarasinghe, Ryoji Kushima, Tetsuo Ushiku, Masato Yozu, Amitabh Srivastava, John R. Goldblum, Rish K. Pai, Gregory Y. Lauwers

Laboratory Medicine and Pathology

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The increasing use of gastrointestinal endoscopic procedures has led to the recognition by histopathologists of non-conventional (or special-type) dysplasias of the gastrointestinal tract. These lesions can be recognised in association with prevalent underlying gastrointestinal conditions, such as Barrett oesophagus, chronic atrophic gastritis, and inflammatory bowel disease. The diagnosis of these special types can be challenging, and their biological behaviours are not fully characterised. The aim of this review is to provide a global view of non-conventional dysplastic lesions observed in the various segments of the tubular gastrointestinal tract and describe their salient features. Furthermore, as the clinical implications of these various subtypes have not been broadly tested in practice and are not represented in most management guidelines, we offer guidance on the best management practices for these lesions.

Original language	English (US)
Pages (from-to)	658-675
Number of pages	18
Journal	Histopathology
Volume	78
Issue number	5
DOIs	https://doi.org/10.1111/his.14294
State	Published - Apr 2021

Keywords

Barrett oesophagus
colon
duodenum
dysplasia
gastric
gastrointestinal
inflammatory bowel disease

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

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10.1111/his.14294

Cite this

Pereira, D., Kővári, B., Brown, I., Chaves, P., Choi, W. T., Clauditz, T., Ghayouri, M., Jiang, K., Miller, G. C., Nakanishi, Y., Kim, K. M., Kim, B. H., Kumarasinghe, M. P., Kushima, R., Ushiku, T., Yozu, M., Srivastava, A., Goldblum, J. R., Pai, R. K., & Lauwers, G. Y. (2021). Non-conventional dysplasias of the tubular gut: a review and illustration of their histomorphological spectrum. Histopathology, 78(5), 658-675. https://doi.org/10.1111/his.14294

Pereira, D, Kővári, B, Brown, I, Chaves, P, Choi, WT, Clauditz, T, Ghayouri, M, Jiang, K, Miller, GC, Nakanishi, Y, Kim, KM, Kim, BH, Kumarasinghe, MP, Kushima, R, Ushiku, T, Yozu, M, Srivastava, A, Goldblum, JR, Pai, RK & Lauwers, GY 2021, 'Non-conventional dysplasias of the tubular gut: a review and illustration of their histomorphological spectrum', Histopathology, vol. 78, no. 5, pp. 658-675. https://doi.org/10.1111/his.14294

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abstract = "The increasing use of gastrointestinal endoscopic procedures has led to the recognition by histopathologists of non-conventional (or special-type) dysplasias of the gastrointestinal tract. These lesions can be recognised in association with prevalent underlying gastrointestinal conditions, such as Barrett oesophagus, chronic atrophic gastritis, and inflammatory bowel disease. The diagnosis of these special types can be challenging, and their biological behaviours are not fully characterised. The aim of this review is to provide a global view of non-conventional dysplastic lesions observed in the various segments of the tubular gastrointestinal tract and describe their salient features. Furthermore, as the clinical implications of these various subtypes have not been broadly tested in practice and are not represented in most management guidelines, we offer guidance on the best management practices for these lesions.",

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AU - Kim, Baek H.

AU - Kumarasinghe, Marian P.

AU - Kushima, Ryoji

AU - Ushiku, Tetsuo

AU - Yozu, Masato

AU - Srivastava, Amitabh

AU - Goldblum, John R.

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AU - Lauwers, Gregory Y.

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Non-conventional dysplasias of the tubular gut: a review and illustration of their histomorphological spectrum

Abstract

Keywords

ASJC Scopus subject areas

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