Newer aspects of carnitine metabolism in uremia

Vincenzo Savica, Menotti Calvani, Paola Benatti, Domenico Santoro, Paolo Monardo, Agostino Mallamace, Rodolfo Savica, Guido Bellinghieri

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

New knowledge on the physiologic role of L-carnitine and on the rationale of its use in patients on maintenance hemodialysis is provided. In particular, carnitine normalizes plasma and muscle carnitine levels and modifies both enzymatic pattern of muscle and morphology of single fibers, improving exercise tolerance. In addition, carnitine reduces erythropoietin requirements, the number of hypotensive episodes, improves ejection fraction, and decreases hospitalization.

Original languageEnglish (US)
Pages (from-to)52-55
Number of pages4
JournalSeminars in Nephrology
Volume26
Issue number1
DOIs
StatePublished - Jan 1 2006
Externally publishedYes

Fingerprint

Carnitine
Uremia
Muscles
Exercise Tolerance
Erythropoietin
Renal Dialysis
Hospitalization
Maintenance

Keywords

  • Carnitine
  • Carnitine acyltransferase
  • Carnitine deficiency
  • Hemodialysis
  • Mitochondria

ASJC Scopus subject areas

  • Nephrology

Cite this

Savica, V., Calvani, M., Benatti, P., Santoro, D., Monardo, P., Mallamace, A., ... Bellinghieri, G. (2006). Newer aspects of carnitine metabolism in uremia. Seminars in Nephrology, 26(1), 52-55. https://doi.org/10.1016/j.semnephrol.2005.06.010

Newer aspects of carnitine metabolism in uremia. / Savica, Vincenzo; Calvani, Menotti; Benatti, Paola; Santoro, Domenico; Monardo, Paolo; Mallamace, Agostino; Savica, Rodolfo; Bellinghieri, Guido.

In: Seminars in Nephrology, Vol. 26, No. 1, 01.01.2006, p. 52-55.

Research output: Contribution to journalArticle

Savica, V, Calvani, M, Benatti, P, Santoro, D, Monardo, P, Mallamace, A, Savica, R & Bellinghieri, G 2006, 'Newer aspects of carnitine metabolism in uremia', Seminars in Nephrology, vol. 26, no. 1, pp. 52-55. https://doi.org/10.1016/j.semnephrol.2005.06.010
Savica V, Calvani M, Benatti P, Santoro D, Monardo P, Mallamace A et al. Newer aspects of carnitine metabolism in uremia. Seminars in Nephrology. 2006 Jan 1;26(1):52-55. https://doi.org/10.1016/j.semnephrol.2005.06.010
Savica, Vincenzo ; Calvani, Menotti ; Benatti, Paola ; Santoro, Domenico ; Monardo, Paolo ; Mallamace, Agostino ; Savica, Rodolfo ; Bellinghieri, Guido. / Newer aspects of carnitine metabolism in uremia. In: Seminars in Nephrology. 2006 ; Vol. 26, No. 1. pp. 52-55.
@article{f449f561255e485fb08124a25c72e5cd,
title = "Newer aspects of carnitine metabolism in uremia",
abstract = "New knowledge on the physiologic role of L-carnitine and on the rationale of its use in patients on maintenance hemodialysis is provided. In particular, carnitine normalizes plasma and muscle carnitine levels and modifies both enzymatic pattern of muscle and morphology of single fibers, improving exercise tolerance. In addition, carnitine reduces erythropoietin requirements, the number of hypotensive episodes, improves ejection fraction, and decreases hospitalization.",
keywords = "Carnitine, Carnitine acyltransferase, Carnitine deficiency, Hemodialysis, Mitochondria",
author = "Vincenzo Savica and Menotti Calvani and Paola Benatti and Domenico Santoro and Paolo Monardo and Agostino Mallamace and Rodolfo Savica and Guido Bellinghieri",
year = "2006",
month = "1",
day = "1",
doi = "10.1016/j.semnephrol.2005.06.010",
language = "English (US)",
volume = "26",
pages = "52--55",
journal = "Seminars in Nephrology",
issn = "0270-9295",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Newer aspects of carnitine metabolism in uremia

AU - Savica, Vincenzo

AU - Calvani, Menotti

AU - Benatti, Paola

AU - Santoro, Domenico

AU - Monardo, Paolo

AU - Mallamace, Agostino

AU - Savica, Rodolfo

AU - Bellinghieri, Guido

PY - 2006/1/1

Y1 - 2006/1/1

N2 - New knowledge on the physiologic role of L-carnitine and on the rationale of its use in patients on maintenance hemodialysis is provided. In particular, carnitine normalizes plasma and muscle carnitine levels and modifies both enzymatic pattern of muscle and morphology of single fibers, improving exercise tolerance. In addition, carnitine reduces erythropoietin requirements, the number of hypotensive episodes, improves ejection fraction, and decreases hospitalization.

AB - New knowledge on the physiologic role of L-carnitine and on the rationale of its use in patients on maintenance hemodialysis is provided. In particular, carnitine normalizes plasma and muscle carnitine levels and modifies both enzymatic pattern of muscle and morphology of single fibers, improving exercise tolerance. In addition, carnitine reduces erythropoietin requirements, the number of hypotensive episodes, improves ejection fraction, and decreases hospitalization.

KW - Carnitine

KW - Carnitine acyltransferase

KW - Carnitine deficiency

KW - Hemodialysis

KW - Mitochondria

UR - http://www.scopus.com/inward/record.url?scp=30444440888&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=30444440888&partnerID=8YFLogxK

U2 - 10.1016/j.semnephrol.2005.06.010

DO - 10.1016/j.semnephrol.2005.06.010

M3 - Article

C2 - 16412827

AN - SCOPUS:30444440888

VL - 26

SP - 52

EP - 55

JO - Seminars in Nephrology

JF - Seminars in Nephrology

SN - 0270-9295

IS - 1

ER -