Neurotransmitter stimulation for retinal prosthesis: The artificial synapse chip

Raymond Iezzi; Paul G. Finlayson

doi:10.1007/978-1-4419-0754-7_9

Neurotransmitter stimulation for retinal prosthesis: The artificial synapse chip

Raymond Iezzi, Paul G. Finlayson

Ophthalmology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

9 Scopus citations

Abstract

Retinal prostheses may one day improve the lives of hundreds of thousands of patients with retinitis pigmentosa (RP) or millions of blind patients with advanced age-related macular degeneration (ARMD), depending on their effectiveness. While considerable progress has been made in electrical stimulation of the retina, herein we explore some possible alternatives to electrical stimulation for retinal prosthesis. Since neurotransmitters normally shape visual responses, some groups have been developing visual prostheses based upon the spatially and temporally controlled delivery of neurotransmitters to the retina. This chapter examines the possibilities for utilizing these chemical messengers, as a means to effectively stimulate retinal ganglion cells and produce vision along established visual information channels.

Original language	English (US)
Title of host publication	Visual Prosthetics
Subtitle of host publication	Physiology, Bioengineering, Rehabilitation
Publisher	Springer US
Pages	173-191
Number of pages	19
ISBN (Print)	9781441907530
DOIs	https://doi.org/10.1007/978-1-4419-0754-7_9
State	Published - 2011

ASJC Scopus subject areas

General Engineering

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10.1007/978-1-4419-0754-7_9

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AB - Retinal prostheses may one day improve the lives of hundreds of thousands of patients with retinitis pigmentosa (RP) or millions of blind patients with advanced age-related macular degeneration (ARMD), depending on their effectiveness. While considerable progress has been made in electrical stimulation of the retina, herein we explore some possible alternatives to electrical stimulation for retinal prosthesis. Since neurotransmitters normally shape visual responses, some groups have been developing visual prostheses based upon the spatially and temporally controlled delivery of neurotransmitters to the retina. This chapter examines the possibilities for utilizing these chemical messengers, as a means to effectively stimulate retinal ganglion cells and produce vision along established visual information channels.

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Neurotransmitter stimulation for retinal prosthesis: The artificial synapse chip

Abstract

ASJC Scopus subject areas

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