Neurosarcoidosis presenting as a cerebellar mass

Gautam Kumar, Caroline A. Kang, Caterina Giannini

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

CASE REPORT: A 74-year-old farmer presented with worsening headaches, gait unsteadiness, and writing difficulties. On examination, he had a tendency to fall to the right and right-sided dysmetria and dysdiadochokinesis. Magnetic resonance imaging initially showed abnormalities in the right cerebellar hemisphere, suggestive of subacute infarct or infiltrating malignancy. Suboccipital craniotomy and biopsy revealed noncaseating granulomas suggestive of sarcoidosis. He was initially treated with steroids and later switched to Infliximab. On follow-up 5 months later, symptoms and imaging had improved. DISCUSSION: Sarcoidosis affects the central nervous system in about 5% of patients. It usually manifests with cranial nerve palsies. It may rarely mimic a tumor as in this patient. Despite the dearth of controlled studies addressing neurosarcoidosis treatment, excellent responses to corticosteroids have been documented. Infliximab has been used as a steroid-sparing agent in neurosarcoidosis. We present this case of neurosarcoidosis presenting as a cerebellar mass to increase awareness of this condition.

Original languageEnglish (US)
Pages (from-to)1373-1376
Number of pages4
JournalJournal of General Internal Medicine
Volume22
Issue number9
DOIs
StatePublished - Sep 2007

Fingerprint

Sarcoidosis
Steroids
Cranial Nerve Diseases
Cerebellar Ataxia
Craniotomy
Granuloma
Gait
Headache
Neoplasms
Adrenal Cortex Hormones
Central Nervous System
Magnetic Resonance Imaging
Biopsy
Neurosarcoidosis
Infliximab
Therapeutics
Farmers

Keywords

  • Cerebellar mass
  • Infliximab
  • Neurosarcoidosis

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Neurosarcoidosis presenting as a cerebellar mass. / Kumar, Gautam; Kang, Caroline A.; Giannini, Caterina.

In: Journal of General Internal Medicine, Vol. 22, No. 9, 09.2007, p. 1373-1376.

Research output: Contribution to journalArticle

Kumar, Gautam ; Kang, Caroline A. ; Giannini, Caterina. / Neurosarcoidosis presenting as a cerebellar mass. In: Journal of General Internal Medicine. 2007 ; Vol. 22, No. 9. pp. 1373-1376.
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