Abstract
Neurosarcoidosis occurs in 3% to 10% of patients with sarcoidosis. Cranial neuropathy and meningeal involvement are the most common manifestations, but any part of the nervous system can be affected. Definite diagnosis requires the presence of noncaseating granuloma in the nervous system, although histopathologic confirmation is often not obtainable. Moderate to high dose of glucocorticoids is the main therapy for neurosarcoidosis. Relapse often occurs after the dose of glucocorticoids is tapered down, often necessitating the use of steroid-sparing immunosuppressive agents.
Original language | English (US) |
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Pages (from-to) | 593-606 |
Number of pages | 14 |
Journal | Rheumatic Disease Clinics of North America |
Volume | 43 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2017 |
Keywords
- Clinical manifestation
- Imaging study
- Neurosarcoidosis
- Outcome
- Sarcoidosis
- Treatment
ASJC Scopus subject areas
- Rheumatology