Necrotizing cutaneous cryoglobulinemic vasculopathy

R. C. Mahabir, C. D. Taylor, W. B. Benny, J. P. Dutz, C. F T Snelling

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This case report highlights the risk of donor-site conversion in the setting of necrotizing cryoglobulinemic vasculopathy. Because no single treatment modality has been shown to be consistently effective, a multidisciplinary approach provides the best prospect for disease control and ulcer healing. Medical therapy through plasma exchange reduces the quantity of cryoglobulins, whereas immunosuppression attempts to reduce the degree and effects of cryoprecipitation. If thorough conservative care fails, consideration for surgical management should include minimizing the size of the split-thickness skin graft donor site because of the high risk of donor-site conversion. Warmed rooms and intravenous fluids and the use of occlusive dressings may reduce the chance of cryoglobulin deposition in the vasculature, a rather unusual complication of cryoglobulinemia.

Original languageEnglish (US)
Pages (from-to)1221-1224
Number of pages4
JournalPlastic and Reconstructive Surgery
Volume107
Issue number5
StatePublished - Apr 15 2001
Externally publishedYes

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Cryoglobulins
Occlusive Dressings
Cryoglobulinemia
Skin
Plasma Exchange
Immunosuppression
Ulcer
Transplants
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Mahabir, R. C., Taylor, C. D., Benny, W. B., Dutz, J. P., & Snelling, C. F. T. (2001). Necrotizing cutaneous cryoglobulinemic vasculopathy. Plastic and Reconstructive Surgery, 107(5), 1221-1224.

Necrotizing cutaneous cryoglobulinemic vasculopathy. / Mahabir, R. C.; Taylor, C. D.; Benny, W. B.; Dutz, J. P.; Snelling, C. F T.

In: Plastic and Reconstructive Surgery, Vol. 107, No. 5, 15.04.2001, p. 1221-1224.

Research output: Contribution to journalArticle

Mahabir, RC, Taylor, CD, Benny, WB, Dutz, JP & Snelling, CFT 2001, 'Necrotizing cutaneous cryoglobulinemic vasculopathy', Plastic and Reconstructive Surgery, vol. 107, no. 5, pp. 1221-1224.
Mahabir RC, Taylor CD, Benny WB, Dutz JP, Snelling CFT. Necrotizing cutaneous cryoglobulinemic vasculopathy. Plastic and Reconstructive Surgery. 2001 Apr 15;107(5):1221-1224.
Mahabir, R. C. ; Taylor, C. D. ; Benny, W. B. ; Dutz, J. P. ; Snelling, C. F T. / Necrotizing cutaneous cryoglobulinemic vasculopathy. In: Plastic and Reconstructive Surgery. 2001 ; Vol. 107, No. 5. pp. 1221-1224.
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