Multiple myeloma terminating in acute eosinophilic leukemia

Koichi Maeda, Ellis J. VanSlyck, Daniel L. VanDyke

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A 71-year-old woman with multiple myeloma was successfully managed for 8 years with melphalan (total dose 2056 mg). She developed a refractory anemia (myelodysplastic state), which terminated in acute eosinophilic leukemia. This form of acute leukemia, induced by chemotherapy, appears to be very rare. The cytogenetic changes, including 5q- and monosomy 7, were similar to those observed in other patients with acute nonlymphocytic leukemia as a secondary malignancy following treatments of other primary tumors.

Original languageEnglish (US)
Pages (from-to)81-89
Number of pages9
JournalCancer Genetics and Cytogenetics
Volume16
Issue number1
DOIs
StatePublished - Mar 1 1985
Externally publishedYes

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Leukemia, Eosinophilic, Acute
Multiple Myeloma
Refractory Anemia
Melphalan
Acute Myeloid Leukemia
Cytogenetics
Neoplasms
Leukemia
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

Multiple myeloma terminating in acute eosinophilic leukemia. / Maeda, Koichi; VanSlyck, Ellis J.; VanDyke, Daniel L.

In: Cancer Genetics and Cytogenetics, Vol. 16, No. 1, 01.03.1985, p. 81-89.

Research output: Contribution to journalArticle

Maeda, Koichi ; VanSlyck, Ellis J. ; VanDyke, Daniel L. / Multiple myeloma terminating in acute eosinophilic leukemia. In: Cancer Genetics and Cytogenetics. 1985 ; Vol. 16, No. 1. pp. 81-89.
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