Multimodal Therapy in the Management of Advanced Penile Cancer

Praful Ravi; Lance C. Pagliaro

doi:10.1016/j.ucl.2016.06.008

Multimodal Therapy in the Management of Advanced Penile Cancer

Praful Ravi, Lance C. Pagliaro

Medical Oncology

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

A multimodal approach to therapy is increasingly used in treating men with advanced penile cancer. Adjuvant chemotherapy improves outcomes in chemotherapy-naïve men with node-positive positive disease, and neoadjuvant chemotherapy can downstage bulky nodal disease sufficiently to permit surgery and has the potential to offer durable long-term survival. However, there remain several unanswered questions in this field, and international collaboration in the form of clinical trials is required to optimize treatment and improve survival in men with advanced penile cancer.

Original language	English (US)
Pages (from-to)	469-479
Number of pages	11
Journal	Urologic Clinics of North America
Volume	43
Issue number	4
DOIs	https://doi.org/10.1016/j.ucl.2016.06.008
State	Published - Nov 1 2016

Keywords

Adjuvant chemotherapy
Neoadjuvant chemotherapy
Penile cancer
Radiotherapy
Survival

ASJC Scopus subject areas

Urology

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10.1016/j.ucl.2016.06.008

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title = "Multimodal Therapy in the Management of Advanced Penile Cancer",

abstract = "A multimodal approach to therapy is increasingly used in treating men with advanced penile cancer. Adjuvant chemotherapy improves outcomes in chemotherapy-na{\"i}ve men with node-positive positive disease, and neoadjuvant chemotherapy can downstage bulky nodal disease sufficiently to permit surgery and has the potential to offer durable long-term survival. However, there remain several unanswered questions in this field, and international collaboration in the form of clinical trials is required to optimize treatment and improve survival in men with advanced penile cancer.",

keywords = "Adjuvant chemotherapy, Neoadjuvant chemotherapy, Penile cancer, Radiotherapy, Survival",

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AU - Pagliaro, Lance C.

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AB - A multimodal approach to therapy is increasingly used in treating men with advanced penile cancer. Adjuvant chemotherapy improves outcomes in chemotherapy-naïve men with node-positive positive disease, and neoadjuvant chemotherapy can downstage bulky nodal disease sufficiently to permit surgery and has the potential to offer durable long-term survival. However, there remain several unanswered questions in this field, and international collaboration in the form of clinical trials is required to optimize treatment and improve survival in men with advanced penile cancer.

KW - Adjuvant chemotherapy

KW - Neoadjuvant chemotherapy

KW - Penile cancer

KW - Radiotherapy

KW - Survival

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Multimodal Therapy in the Management of Advanced Penile Cancer

Abstract

Keywords

ASJC Scopus subject areas

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