Multifocal Urinary Bladder Paragangliomas with Negative 68Ga-DOTATATE Uptake and Positive 123I-MIBG Uptake

Laura A. Parra, Scott K. Swanson, Marcela A. Salomao, Ming Yang

Research output: Contribution to journalArticle

Abstract

We report a case of an adult male patient with multifocal urinary bladder paragangliomas, which were negative on 68Ga-DOTATATE PET/CT scan, but positive on 123I-MIBG SPECT/CT scan. While the 68Ga-DOTA analog PET/CT exhibits superior performance in diagnosis and staging of pheochromocytoma and paraganglioma, our case demonstrates negative somatostatin receptor expression in this rare entity and indicates that 123I-MIBG SPECT/CT still plays a vital role in characterization of bladder paraganglioma.

Original languageEnglish (US)
Pages (from-to)E156-E157
JournalClinical nuclear medicine
Volume45
Issue number3
DOIs
StatePublished - Mar 1 2020

Keywords

  • DOTATATE
  • MIBG
  • PETCT
  • bladder paraganglioma
  • somatostatin receptor

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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