Multidirectional high-moment encoding in phase contrast MRI

Nicholas R. Zwart, James Pipe

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The use of phase contrast MRI to measure vascular flow provides a unique method for acquiring quantitative estimates of flow as well as morphological imaging. The quantitative aspects of phase contrast magnetic resonance angiography (PC-MRA) provide unique relationships between measurement parameters and resulting signal to noise ratio of the velocity measurements. This article introduces a new method to exploit these relationships providing increased efficiency, and therefore, higher vessel conspicuity. Signal to noise ratio gains in high-moment PC-MRA are limited by the ability to unalias phase measurements that fall outside the -π to π interval. Unaliasing phase on a per pixel basis is limited by errors in the measurements due to noise and intravoxel flow distributions. Current dual-VENC methods have been shown to be robust to these errors and provide high velocity to noise ratio gains, however, the collection of a required high-VENC set can be inefficient. The presented method provides more time efficient gains in velocity to noise ratio compared to a dual-VENC approach by eliminating the high-VENC acquisitions and using shared information between nonorthogonal measurements. Simulations, phantom, and in vivo angiography are used to characterize the noise performance of each method. The velocity to noise ratio efficiency of the proposed method is shown to be ∼1.7 times greater than the dual-VENC method at the same gradient moment.

Original languageEnglish (US)
Pages (from-to)1553-1564
Number of pages12
JournalMagnetic Resonance in Medicine
Volume69
Issue number6
DOIs
StatePublished - Jun 1 2013
Externally publishedYes

Fingerprint

Noise
Magnetic Resonance Angiography
Signal-To-Noise Ratio
Blood Vessels
Angiography

Keywords

  • high moment
  • multiple-VENC
  • phase contrast
  • velocity quantitation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Multidirectional high-moment encoding in phase contrast MRI. / Zwart, Nicholas R.; Pipe, James.

In: Magnetic Resonance in Medicine, Vol. 69, No. 6, 01.06.2013, p. 1553-1564.

Research output: Contribution to journalArticle

@article{3e0eabe64f2843fb890a92164b0f2905,
title = "Multidirectional high-moment encoding in phase contrast MRI",
abstract = "The use of phase contrast MRI to measure vascular flow provides a unique method for acquiring quantitative estimates of flow as well as morphological imaging. The quantitative aspects of phase contrast magnetic resonance angiography (PC-MRA) provide unique relationships between measurement parameters and resulting signal to noise ratio of the velocity measurements. This article introduces a new method to exploit these relationships providing increased efficiency, and therefore, higher vessel conspicuity. Signal to noise ratio gains in high-moment PC-MRA are limited by the ability to unalias phase measurements that fall outside the -π to π interval. Unaliasing phase on a per pixel basis is limited by errors in the measurements due to noise and intravoxel flow distributions. Current dual-VENC methods have been shown to be robust to these errors and provide high velocity to noise ratio gains, however, the collection of a required high-VENC set can be inefficient. The presented method provides more time efficient gains in velocity to noise ratio compared to a dual-VENC approach by eliminating the high-VENC acquisitions and using shared information between nonorthogonal measurements. Simulations, phantom, and in vivo angiography are used to characterize the noise performance of each method. The velocity to noise ratio efficiency of the proposed method is shown to be ∼1.7 times greater than the dual-VENC method at the same gradient moment.",
keywords = "high moment, multiple-VENC, phase contrast, velocity quantitation",
author = "Zwart, {Nicholas R.} and James Pipe",
year = "2013",
month = "6",
day = "1",
doi = "10.1002/mrm.24390",
language = "English (US)",
volume = "69",
pages = "1553--1564",
journal = "Magnetic Resonance in Medicine",
issn = "0740-3194",
publisher = "John Wiley and Sons Inc.",
number = "6",

}

TY - JOUR

T1 - Multidirectional high-moment encoding in phase contrast MRI

AU - Zwart, Nicholas R.

AU - Pipe, James

PY - 2013/6/1

Y1 - 2013/6/1

N2 - The use of phase contrast MRI to measure vascular flow provides a unique method for acquiring quantitative estimates of flow as well as morphological imaging. The quantitative aspects of phase contrast magnetic resonance angiography (PC-MRA) provide unique relationships between measurement parameters and resulting signal to noise ratio of the velocity measurements. This article introduces a new method to exploit these relationships providing increased efficiency, and therefore, higher vessel conspicuity. Signal to noise ratio gains in high-moment PC-MRA are limited by the ability to unalias phase measurements that fall outside the -π to π interval. Unaliasing phase on a per pixel basis is limited by errors in the measurements due to noise and intravoxel flow distributions. Current dual-VENC methods have been shown to be robust to these errors and provide high velocity to noise ratio gains, however, the collection of a required high-VENC set can be inefficient. The presented method provides more time efficient gains in velocity to noise ratio compared to a dual-VENC approach by eliminating the high-VENC acquisitions and using shared information between nonorthogonal measurements. Simulations, phantom, and in vivo angiography are used to characterize the noise performance of each method. The velocity to noise ratio efficiency of the proposed method is shown to be ∼1.7 times greater than the dual-VENC method at the same gradient moment.

AB - The use of phase contrast MRI to measure vascular flow provides a unique method for acquiring quantitative estimates of flow as well as morphological imaging. The quantitative aspects of phase contrast magnetic resonance angiography (PC-MRA) provide unique relationships between measurement parameters and resulting signal to noise ratio of the velocity measurements. This article introduces a new method to exploit these relationships providing increased efficiency, and therefore, higher vessel conspicuity. Signal to noise ratio gains in high-moment PC-MRA are limited by the ability to unalias phase measurements that fall outside the -π to π interval. Unaliasing phase on a per pixel basis is limited by errors in the measurements due to noise and intravoxel flow distributions. Current dual-VENC methods have been shown to be robust to these errors and provide high velocity to noise ratio gains, however, the collection of a required high-VENC set can be inefficient. The presented method provides more time efficient gains in velocity to noise ratio compared to a dual-VENC approach by eliminating the high-VENC acquisitions and using shared information between nonorthogonal measurements. Simulations, phantom, and in vivo angiography are used to characterize the noise performance of each method. The velocity to noise ratio efficiency of the proposed method is shown to be ∼1.7 times greater than the dual-VENC method at the same gradient moment.

KW - high moment

KW - multiple-VENC

KW - phase contrast

KW - velocity quantitation

UR - http://www.scopus.com/inward/record.url?scp=84878112858&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878112858&partnerID=8YFLogxK

U2 - 10.1002/mrm.24390

DO - 10.1002/mrm.24390

M3 - Article

C2 - 22760964

AN - SCOPUS:84878112858

VL - 69

SP - 1553

EP - 1564

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

SN - 0740-3194

IS - 6

ER -