Multicenter study of the safety and effects of magnetic resonance imaging in patients with coronary sinus left ventricular pacing leads

Seth H. Sheldon, T. Jared Bunch, Gregory A. Cogert, Nancy G. Acker, Connie M. Dalzell, John V. Higgins, Raul Emilio Espinosa, Samuel J Asirvatham, Yong-Mei Cha, Joel P. Felmlee, Robert E. Watson, Jeffrey L. Anderson, Miriam H. Brooks, Jeffrey S. Osborn, Paul Andrew Friedman

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Background Magnetic resonance imaging (MRI) in patients with left ventricular (LV) leads may cause tissue or lead heating, dislodgment, venous damage, or lead dysfunction. Objective The purpose of this study was to determine the safety of MRI in patients with LV pacing leads. Methods Prospective data on patients with coronary sinus LV leads undergoing clinically indicated MRI at 3 institutions were collected. Patients were not pacemaker-dependent. Scans were performed under pacing nurse, technician, radiologist, and physicist supervision using continuous vital sign, pulse oximetry, and ECG monitoring and a 1.5-T scanner with specific absorption rate <1.5 W/kg. Devices were interrogated pre- and post-MRI, programmed to asynchronous or inhibition mode with tachyarrhythmia therapies off (if present), and reprogrammed to their original settings post-MRI. Results MRI scans (n = 42) were performed in 40 patients with non-MRI conditional LV leads between 2005 and 2013 (mean age 67 ± 9 years, n = 16 [40%] women, median lead implant duration 740 days with interquartile range 125-1173 days). MRIs were performed on the head/neck/spine (n = 35 [83%]), lower extremities (n = 4 [10%]), chest (n = 2 [5%]), and abdomen (n = 1 [2%]). There were no overall differences in pre- and post-MRI interrogation LV lead sensing (12.4 ± 6.2 mV vs 12.9 ± 6.7 mV, P =.38), impedance (724 ± 294 Ω vs 718 ± 312 Ω, P =.67), or threshold (1.4 ± 1.1 V vs 1.4 ± 1.0 V, P =.91). No individual LV lead changes required intervention. Conclusion MRI scanning was performed safely in non-pacemaker-dependent patients with coronary sinus LV leads who were carefully monitored during imaging without clinically significant adverse effect on LV lead function.

Original languageEnglish (US)
Pages (from-to)345-349
Number of pages5
JournalHeart Rhythm
Volume12
Issue number2
DOIs
StatePublished - Feb 1 2015

Fingerprint

Coronary Sinus
Multicenter Studies
Magnetic Resonance Imaging
Safety
Oximetry
Vital Signs
Electric Impedance
Left Ventricular Function
Tachycardia
Abdomen
Heating
Lower Extremity
Electrocardiography
Spine
Neck
Thorax
Nurses
Head
Lead
Equipment and Supplies

Keywords

  • Cardiacimplantable electronic device
  • Cardiacresynchronizationdevice
  • Coronary sinus
  • Implantablecardioverter-defibrillator
  • Magnetic resonanceimaging
  • Safety

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Multicenter study of the safety and effects of magnetic resonance imaging in patients with coronary sinus left ventricular pacing leads. / Sheldon, Seth H.; Bunch, T. Jared; Cogert, Gregory A.; Acker, Nancy G.; Dalzell, Connie M.; Higgins, John V.; Espinosa, Raul Emilio; Asirvatham, Samuel J; Cha, Yong-Mei; Felmlee, Joel P.; Watson, Robert E.; Anderson, Jeffrey L.; Brooks, Miriam H.; Osborn, Jeffrey S.; Friedman, Paul Andrew.

In: Heart Rhythm, Vol. 12, No. 2, 01.02.2015, p. 345-349.

Research output: Contribution to journalArticle

Sheldon, SH, Bunch, TJ, Cogert, GA, Acker, NG, Dalzell, CM, Higgins, JV, Espinosa, RE, Asirvatham, SJ, Cha, Y-M, Felmlee, JP, Watson, RE, Anderson, JL, Brooks, MH, Osborn, JS & Friedman, PA 2015, 'Multicenter study of the safety and effects of magnetic resonance imaging in patients with coronary sinus left ventricular pacing leads', Heart Rhythm, vol. 12, no. 2, pp. 345-349. https://doi.org/10.1016/j.hrthm.2014.11.037
Sheldon, Seth H. ; Bunch, T. Jared ; Cogert, Gregory A. ; Acker, Nancy G. ; Dalzell, Connie M. ; Higgins, John V. ; Espinosa, Raul Emilio ; Asirvatham, Samuel J ; Cha, Yong-Mei ; Felmlee, Joel P. ; Watson, Robert E. ; Anderson, Jeffrey L. ; Brooks, Miriam H. ; Osborn, Jeffrey S. ; Friedman, Paul Andrew. / Multicenter study of the safety and effects of magnetic resonance imaging in patients with coronary sinus left ventricular pacing leads. In: Heart Rhythm. 2015 ; Vol. 12, No. 2. pp. 345-349.
@article{d284f170864f495eb9305a991a8b27c5,
title = "Multicenter study of the safety and effects of magnetic resonance imaging in patients with coronary sinus left ventricular pacing leads",
abstract = "Background Magnetic resonance imaging (MRI) in patients with left ventricular (LV) leads may cause tissue or lead heating, dislodgment, venous damage, or lead dysfunction. Objective The purpose of this study was to determine the safety of MRI in patients with LV pacing leads. Methods Prospective data on patients with coronary sinus LV leads undergoing clinically indicated MRI at 3 institutions were collected. Patients were not pacemaker-dependent. Scans were performed under pacing nurse, technician, radiologist, and physicist supervision using continuous vital sign, pulse oximetry, and ECG monitoring and a 1.5-T scanner with specific absorption rate <1.5 W/kg. Devices were interrogated pre- and post-MRI, programmed to asynchronous or inhibition mode with tachyarrhythmia therapies off (if present), and reprogrammed to their original settings post-MRI. Results MRI scans (n = 42) were performed in 40 patients with non-MRI conditional LV leads between 2005 and 2013 (mean age 67 ± 9 years, n = 16 [40{\%}] women, median lead implant duration 740 days with interquartile range 125-1173 days). MRIs were performed on the head/neck/spine (n = 35 [83{\%}]), lower extremities (n = 4 [10{\%}]), chest (n = 2 [5{\%}]), and abdomen (n = 1 [2{\%}]). There were no overall differences in pre- and post-MRI interrogation LV lead sensing (12.4 ± 6.2 mV vs 12.9 ± 6.7 mV, P =.38), impedance (724 ± 294 Ω vs 718 ± 312 Ω, P =.67), or threshold (1.4 ± 1.1 V vs 1.4 ± 1.0 V, P =.91). No individual LV lead changes required intervention. Conclusion MRI scanning was performed safely in non-pacemaker-dependent patients with coronary sinus LV leads who were carefully monitored during imaging without clinically significant adverse effect on LV lead function.",
keywords = "Cardiacimplantable electronic device, Cardiacresynchronizationdevice, Coronary sinus, Implantablecardioverter-defibrillator, Magnetic resonanceimaging, Safety",
author = "Sheldon, {Seth H.} and Bunch, {T. Jared} and Cogert, {Gregory A.} and Acker, {Nancy G.} and Dalzell, {Connie M.} and Higgins, {John V.} and Espinosa, {Raul Emilio} and Asirvatham, {Samuel J} and Yong-Mei Cha and Felmlee, {Joel P.} and Watson, {Robert E.} and Anderson, {Jeffrey L.} and Brooks, {Miriam H.} and Osborn, {Jeffrey S.} and Friedman, {Paul Andrew}",
year = "2015",
month = "2",
day = "1",
doi = "10.1016/j.hrthm.2014.11.037",
language = "English (US)",
volume = "12",
pages = "345--349",
journal = "Heart Rhythm",
issn = "1547-5271",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Multicenter study of the safety and effects of magnetic resonance imaging in patients with coronary sinus left ventricular pacing leads

AU - Sheldon, Seth H.

AU - Bunch, T. Jared

AU - Cogert, Gregory A.

AU - Acker, Nancy G.

AU - Dalzell, Connie M.

AU - Higgins, John V.

AU - Espinosa, Raul Emilio

AU - Asirvatham, Samuel J

AU - Cha, Yong-Mei

AU - Felmlee, Joel P.

AU - Watson, Robert E.

AU - Anderson, Jeffrey L.

AU - Brooks, Miriam H.

AU - Osborn, Jeffrey S.

AU - Friedman, Paul Andrew

PY - 2015/2/1

Y1 - 2015/2/1

N2 - Background Magnetic resonance imaging (MRI) in patients with left ventricular (LV) leads may cause tissue or lead heating, dislodgment, venous damage, or lead dysfunction. Objective The purpose of this study was to determine the safety of MRI in patients with LV pacing leads. Methods Prospective data on patients with coronary sinus LV leads undergoing clinically indicated MRI at 3 institutions were collected. Patients were not pacemaker-dependent. Scans were performed under pacing nurse, technician, radiologist, and physicist supervision using continuous vital sign, pulse oximetry, and ECG monitoring and a 1.5-T scanner with specific absorption rate <1.5 W/kg. Devices were interrogated pre- and post-MRI, programmed to asynchronous or inhibition mode with tachyarrhythmia therapies off (if present), and reprogrammed to their original settings post-MRI. Results MRI scans (n = 42) were performed in 40 patients with non-MRI conditional LV leads between 2005 and 2013 (mean age 67 ± 9 years, n = 16 [40%] women, median lead implant duration 740 days with interquartile range 125-1173 days). MRIs were performed on the head/neck/spine (n = 35 [83%]), lower extremities (n = 4 [10%]), chest (n = 2 [5%]), and abdomen (n = 1 [2%]). There were no overall differences in pre- and post-MRI interrogation LV lead sensing (12.4 ± 6.2 mV vs 12.9 ± 6.7 mV, P =.38), impedance (724 ± 294 Ω vs 718 ± 312 Ω, P =.67), or threshold (1.4 ± 1.1 V vs 1.4 ± 1.0 V, P =.91). No individual LV lead changes required intervention. Conclusion MRI scanning was performed safely in non-pacemaker-dependent patients with coronary sinus LV leads who were carefully monitored during imaging without clinically significant adverse effect on LV lead function.

AB - Background Magnetic resonance imaging (MRI) in patients with left ventricular (LV) leads may cause tissue or lead heating, dislodgment, venous damage, or lead dysfunction. Objective The purpose of this study was to determine the safety of MRI in patients with LV pacing leads. Methods Prospective data on patients with coronary sinus LV leads undergoing clinically indicated MRI at 3 institutions were collected. Patients were not pacemaker-dependent. Scans were performed under pacing nurse, technician, radiologist, and physicist supervision using continuous vital sign, pulse oximetry, and ECG monitoring and a 1.5-T scanner with specific absorption rate <1.5 W/kg. Devices were interrogated pre- and post-MRI, programmed to asynchronous or inhibition mode with tachyarrhythmia therapies off (if present), and reprogrammed to their original settings post-MRI. Results MRI scans (n = 42) were performed in 40 patients with non-MRI conditional LV leads between 2005 and 2013 (mean age 67 ± 9 years, n = 16 [40%] women, median lead implant duration 740 days with interquartile range 125-1173 days). MRIs were performed on the head/neck/spine (n = 35 [83%]), lower extremities (n = 4 [10%]), chest (n = 2 [5%]), and abdomen (n = 1 [2%]). There were no overall differences in pre- and post-MRI interrogation LV lead sensing (12.4 ± 6.2 mV vs 12.9 ± 6.7 mV, P =.38), impedance (724 ± 294 Ω vs 718 ± 312 Ω, P =.67), or threshold (1.4 ± 1.1 V vs 1.4 ± 1.0 V, P =.91). No individual LV lead changes required intervention. Conclusion MRI scanning was performed safely in non-pacemaker-dependent patients with coronary sinus LV leads who were carefully monitored during imaging without clinically significant adverse effect on LV lead function.

KW - Cardiacimplantable electronic device

KW - Cardiacresynchronizationdevice

KW - Coronary sinus

KW - Implantablecardioverter-defibrillator

KW - Magnetic resonanceimaging

KW - Safety

UR - http://www.scopus.com/inward/record.url?scp=84921044573&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84921044573&partnerID=8YFLogxK

U2 - 10.1016/j.hrthm.2014.11.037

DO - 10.1016/j.hrthm.2014.11.037

M3 - Article

C2 - 25433144

AN - SCOPUS:84921044573

VL - 12

SP - 345

EP - 349

JO - Heart Rhythm

JF - Heart Rhythm

SN - 1547-5271

IS - 2

ER -