MR gradient echo imaging of intravascular blood oxygenation: T2* determination in the presence of flow

Daisy Chien, David L. Levin, Charles M. Anderson

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

The T2* relaxation time of blood varies with its oxygen saturation. To evaluate the feasibility of imaging intravascular blood oxygenation in humans using a conventional 1.5T MR system, we have implemented a method to measure T2* of blood despite the presence of pulsatile flow. The method was tested in a) stationary and flow phantoms, b) blood samples at different levels of oxygen saturation, and c) a human hypoxia model. Our results demonstrate the ability of cardiac‐triggered, flow compensated gradient echo imaging to obtain reproducible T2* measurements of flowing blood in vivo.

Original languageEnglish (US)
Pages (from-to)540-545
Number of pages6
JournalMagnetic Resonance in Medicine
Volume32
Issue number4
DOIs
StatePublished - Oct 1994

Keywords

  • blood oxygenation
  • flow
  • magnetic resonance
  • magnetic susceptibility

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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