The T2* relaxation time of blood varies with its oxygen saturation. To evaluate the feasibility of imaging intravascular blood oxygenation in humans using a conventional 1.5T MR system, we have implemented a method to measure T2* of blood despite the presence of pulsatile flow. The method was tested in a) stationary and flow phantoms, b) blood samples at different levels of oxygen saturation, and c) a human hypoxia model. Our results demonstrate the ability of cardiac‐triggered, flow compensated gradient echo imaging to obtain reproducible T2* measurements of flowing blood in vivo.
- blood oxygenation
- magnetic resonance
- magnetic susceptibility
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging