Motoring around the Golgi

Victoria J. Allan, Heather M. Thompson, Mark A. McNiven

Research output: Contribution to journalReview article

160 Scopus citations

Abstract

The Golgi apparatus is a dynamic organelle through which nascent secretory and transmembrane proteins are transported, post-translationally modified and finally packaged into carrier vesicles for transport along the cytoskeleton to a variety of destinations. In the past decade, studies have shown that a number of 'molecular motors' are involved in maintaining the proper structure and function of the Golgi apparatus. Here, we review just some of the many functions performed by these mechanochemical enzymes - dyneins, kinesins, myosins and dynamin - in relation to the Golgi apparatus.

Original languageEnglish (US)
Pages (from-to)E236-E242
JournalNature Cell Biology
Volume4
Issue number10
DOIs
StatePublished - Oct 2002

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ASJC Scopus subject areas

  • Cell Biology

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