Monte carlo simulation to determine conditions for optical molecular imaging of vascular disease

Mambidzeni Madzivire, Christopher Riederer, James Greenleaf

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Atherosclerosis is a significant contributor to cardiovascular disease, which is a leading cause of death in the United States. Optical imaging is emerging as a promising molecular imaging tool to detect the biomarkers of vascular disease and plaque vulnerability. We describe a Monte Carlo method of investigating the use of targeted fluorescent nanoparticles as a reporter agent for optical molecular imaging. In particular, we used the model to provide insight into the optimum excitation and emission wavelengths for in vivo imaging in the presence of blood and autofluorescence.

Original languageEnglish (US)
Title of host publication2008 5th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, Proceedings, ISBI
Pages169-172
Number of pages4
DOIs
StatePublished - Sep 10 2008
Event2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI - Paris, France
Duration: May 14 2008May 17 2008

Publication series

Name2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI

Other

Other2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
CountryFrance
CityParis
Period5/14/085/17/08

Keywords

  • Atherosclerosis
  • Molecular imaging
  • Monte Carlo
  • Optical imaging
  • Quantum dots

ASJC Scopus subject areas

  • Biomedical Engineering

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