Monte carlo simulation to determine conditions for optical molecular imaging of vascular disease

Mambidzeni Madzivire, Christopher Riederer, James F Greenleaf

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Atherosclerosis is a significant contributor to cardiovascular disease, which is a leading cause of death in the United States. Optical imaging is emerging as a promising molecular imaging tool to detect the biomarkers of vascular disease and plaque vulnerability. We describe a Monte Carlo method of investigating the use of targeted fluorescent nanoparticles as a reporter agent for optical molecular imaging. In particular, we used the model to provide insight into the optimum excitation and emission wavelengths for in vivo imaging in the presence of blood and autofluorescence.

Original languageEnglish (US)
Title of host publication2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI
Pages169-172
Number of pages4
DOIs
StatePublished - 2008
Event2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI - Paris, France
Duration: May 14 2008May 17 2008

Other

Other2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
CountryFrance
CityParis
Period5/14/085/17/08

Fingerprint

Molecular imaging
Imaging techniques
Biomarkers
Blood
Monte Carlo methods
Nanoparticles
Wavelength
Monte Carlo simulation

Keywords

  • Atherosclerosis
  • Molecular imaging
  • Monte Carlo
  • Optical imaging
  • Quantum dots

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Madzivire, M., Riederer, C., & Greenleaf, J. F. (2008). Monte carlo simulation to determine conditions for optical molecular imaging of vascular disease. In 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI (pp. 169-172). [4540959] https://doi.org/10.1109/ISBI.2008.4540959

Monte carlo simulation to determine conditions for optical molecular imaging of vascular disease. / Madzivire, Mambidzeni; Riederer, Christopher; Greenleaf, James F.

2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI. 2008. p. 169-172 4540959.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Madzivire, M, Riederer, C & Greenleaf, JF 2008, Monte carlo simulation to determine conditions for optical molecular imaging of vascular disease. in 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI., 4540959, pp. 169-172, 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI, Paris, France, 5/14/08. https://doi.org/10.1109/ISBI.2008.4540959
Madzivire M, Riederer C, Greenleaf JF. Monte carlo simulation to determine conditions for optical molecular imaging of vascular disease. In 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI. 2008. p. 169-172. 4540959 https://doi.org/10.1109/ISBI.2008.4540959
Madzivire, Mambidzeni ; Riederer, Christopher ; Greenleaf, James F. / Monte carlo simulation to determine conditions for optical molecular imaging of vascular disease. 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI. 2008. pp. 169-172
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