Monocyte Metabolic Activation in Patients with Rheumatoid Arthritis

N. E. Kay, S. D. Douglas

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Monocytes isolated from patients with active rheumatoid arthritis had elevated hexose monophosphate shunt (HMP) levels. Metabolic activity of blood monocytes incubated with rheumatoid sera was assessed by measuring hexose monophosphate shunt (HMP) levels. Sera from patients with rheumatoid arthritis enhanced HMP shunt activity of normal monocytes. These findings suggest that blood monocytes may be activated by circulating components present in rheumatoid sera.

Original languageEnglish (US)
Pages (from-to)303-306
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume161
Issue number3
DOIs
StatePublished - Jul 1979

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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