The term monoclonal gammopathy of undetermined significance (MGUS) denotes the presence of a monoclonal protein (M protein) in persons without evidence of multiple myeloma (MM), Waldenström's macroglobulinemia (WM), AL amyloidosis (AL), or other related diseases. MGUS is characterized by a serum M-protein concentration of less than 3.0 g/dL; less than 10 % clonal plasma cells in the bone marrow; and the absence of end-organ damage (CRAB-hypercalcemia, renal insufficiency, anemia, and bone lesions) related to the plasma cell proliferative disorder [1-4].
- Long-term outcome of MGUS
- MGUS association with other diseases
- MGUS prevalence
- Risk factors for progression of MGUS
- Variants of MGUS
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