Molecular genetics of soft-tissue sarcomas: A brief overview for clinical oncologists

Jorge Torres-Mora, Karen J. Fritchie, Steven I. Robinson, Andre M. Oliveira

Research output: Contribution to journalReview article

4 Scopus citations

Abstract

Soft-tissue sarcomas (STSs) are a heterogeneous group of tumors with distinct lines of differentiation and biologic behavior. Currently, histological analysis is still the main diagnostic approach for the classification of STSs. However, ancillary molecular genetic methods are becoming increasingly important for diagnostic confirmation and therapeutic considerations. Herein, we provide a brief overview of clinically relevant molecular abnormalities of STSs for the general clinical oncologist.

Original languageEnglish (US)
Pages (from-to)73-79
Number of pages7
JournalCancer Journal (United States)
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2014

Keywords

  • Soft-tissue sarcomas (STSs)
  • ancillary molecular genetic methods
  • classification
  • histological analysis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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