Molecular genetics of soft-tissue sarcomas: A brief overview for clinical oncologists

Jorge Torres-Mora, Karen J. Fritchie, Steven Robinson, Andre M. Oliveira

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Soft-tissue sarcomas (STSs) are a heterogeneous group of tumors with distinct lines of differentiation and biologic behavior. Currently, histological analysis is still the main diagnostic approach for the classification of STSs. However, ancillary molecular genetic methods are becoming increasingly important for diagnostic confirmation and therapeutic considerations. Herein, we provide a brief overview of clinically relevant molecular abnormalities of STSs for the general clinical oncologist.

Original languageEnglish (US)
Pages (from-to)73-79
Number of pages7
JournalCancer Journal (United States)
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

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Sarcoma
Molecular Biology
Oncologists
Neoplasms
Therapeutics

Keywords

  • ancillary molecular genetic methods
  • classification
  • histological analysis
  • Soft-tissue sarcomas (STSs)

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Molecular genetics of soft-tissue sarcomas : A brief overview for clinical oncologists. / Torres-Mora, Jorge; Fritchie, Karen J.; Robinson, Steven; Oliveira, Andre M.

In: Cancer Journal (United States), Vol. 20, No. 1, 01.01.2014, p. 73-79.

Research output: Contribution to journalReview article

Torres-Mora, Jorge ; Fritchie, Karen J. ; Robinson, Steven ; Oliveira, Andre M. / Molecular genetics of soft-tissue sarcomas : A brief overview for clinical oncologists. In: Cancer Journal (United States). 2014 ; Vol. 20, No. 1. pp. 73-79.
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