Mild cognitive impairment: When is it a precursor to Alzheimer's disease?

Y. Shah, E. G. Tangalos, R. C. Petersen

Research output: Contribution to journalReview articlepeer-review

100 Scopus citations


There is good evidence suggesting that onset of Alzheimer's disease is commonly preceded by an interim phase known as mild cognitive impairment (MCI). Persons who experience this condition are at increased risk for the development of Alzheimer's disease. Diagnosing MCI involves excluding other morbidities and determining whether the patient meets predefined assessment criteria. There is no treatment for the prevention of MCI, but an understanding of the condition can improve patient management. Several clinical trials are underway to investigate potential potential MCI agents.

Original languageEnglish (US)
Pages (from-to)62-68
Number of pages7
Issue number9
StatePublished - 2000

ASJC Scopus subject areas

  • Geriatrics and Gerontology


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