Micromachined "side-viewing" optical sensor probe for detection of esophageal cancers

A. Garcia-Uribe; K. C. Balareddy; J. Zou; A. K. Wojcik; K. K. Wang; L. V. Wang

doi:10.1016/j.sna.2008.11.008

Micromachined "side-viewing" optical sensor probe for detection of esophageal cancers

A. Garcia-Uribe, K. C. Balareddy, J. Zou, A. K. Wojcik, K. K. Wang, L. V. Wang

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with "side viewing" capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.

Original language	English (US)
Pages (from-to)	144-150
Number of pages	7
Journal	Sensors and Actuators, A: Physical
Volume	150
Issue number	1
DOIs	https://doi.org/10.1016/j.sna.2008.11.008
State	Published - Mar 16 2009

Keywords

Diffuse reflectance
Esophageal cancer
Micromachined probe
Oblique incidence

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Instrumentation
Condensed Matter Physics
Surfaces, Coatings and Films
Metals and Alloys
Electrical and Electronic Engineering

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10.1016/j.sna.2008.11.008

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title = "Micromachined {"}side-viewing{"} optical sensor probe for detection of esophageal cancers",

abstract = "In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with {"}side viewing{"} capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.",

keywords = "Diffuse reflectance, Esophageal cancer, Micromachined probe, Oblique incidence",

author = "A. Garcia-Uribe and Balareddy, {K. C.} and J. Zou and Wojcik, {A. K.} and Wang, {K. K.} and Wang, {L. V.}",

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T1 - Micromachined "side-viewing" optical sensor probe for detection of esophageal cancers

AU - Garcia-Uribe, A.

AU - Balareddy, K. C.

AU - Zou, J.

AU - Wojcik, A. K.

AU - Wang, K. K.

AU - Wang, L. V.

N1 - Funding Information: This project is partially supported by National Institutes of Health under contract R01 CA106728.

PY - 2009/3/16

Y1 - 2009/3/16

N2 - In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with "side viewing" capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.

AB - In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with "side viewing" capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.

KW - Diffuse reflectance

KW - Esophageal cancer

KW - Micromachined probe

KW - Oblique incidence

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Micromachined "side-viewing" optical sensor probe for detection of esophageal cancers

Abstract

Keywords

ASJC Scopus subject areas

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