Micromachined "side-viewing" optical sensor probe for detection of esophageal cancers

A. Garcia-Uribe, K. C. Balareddy, J. Zou, A. K. Wojcik, K. K. Wang, L. V. Wang

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with "side viewing" capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.

Original languageEnglish (US)
Pages (from-to)144-150
Number of pages7
JournalSensors and Actuators, A: Physical
Volume150
Issue number1
DOIs
StatePublished - Mar 16 2009

Keywords

  • Diffuse reflectance
  • Esophageal cancer
  • Micromachined probe
  • Oblique incidence

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering

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