Methods for the assessment of small-bowel and colonic transit

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Transit assessment of the small intestine and colon is relevant in the study of physiology, pathophysiology, and pharmacodynamics, and there is increasing use of small-bowel and colonic transit measurements in clinical practice as well. The main methods that are applied in clinical practice are substrate-hydrogen breath tests for small-bowel transit and radiopaque markers for colonic transit. Over the past 2-3 decades, scintigraphy has become the preferred standard in research studies, particularly for studies of pathophysiology and pharmacodynamics. New approaches include experimental stable isotope measurement of orocecal transit and the recently approved method using a wireless motility capsule that is validated as an accurate measurement of small-bowel and colonic transit.

Original languageEnglish (US)
Pages (from-to)113-123
Number of pages11
JournalSeminars in Nuclear Medicine
Volume42
Issue number2
DOIs
StatePublished - Mar 2012

Fingerprint

Breath Tests
Isotopes
Radionuclide Imaging
Small Intestine
Capsules
Hydrogen
Colon
Research

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Methods for the assessment of small-bowel and colonic transit. / Szarka, Lawrence; Camilleri, Michael.

In: Seminars in Nuclear Medicine, Vol. 42, No. 2, 03.2012, p. 113-123.

Research output: Contribution to journalArticle

@article{116a99e6570149ee8502b815dc311f52,
title = "Methods for the assessment of small-bowel and colonic transit",
abstract = "Transit assessment of the small intestine and colon is relevant in the study of physiology, pathophysiology, and pharmacodynamics, and there is increasing use of small-bowel and colonic transit measurements in clinical practice as well. The main methods that are applied in clinical practice are substrate-hydrogen breath tests for small-bowel transit and radiopaque markers for colonic transit. Over the past 2-3 decades, scintigraphy has become the preferred standard in research studies, particularly for studies of pathophysiology and pharmacodynamics. New approaches include experimental stable isotope measurement of orocecal transit and the recently approved method using a wireless motility capsule that is validated as an accurate measurement of small-bowel and colonic transit.",
author = "Lawrence Szarka and Michael Camilleri",
year = "2012",
month = "3",
doi = "10.1053/j.semnuclmed.2011.10.004",
language = "English (US)",
volume = "42",
pages = "113--123",
journal = "Seminars in Nuclear Medicine",
issn = "0001-2998",
publisher = "W.B. Saunders Ltd",
number = "2",

}

TY - JOUR

T1 - Methods for the assessment of small-bowel and colonic transit

AU - Szarka, Lawrence

AU - Camilleri, Michael

PY - 2012/3

Y1 - 2012/3

N2 - Transit assessment of the small intestine and colon is relevant in the study of physiology, pathophysiology, and pharmacodynamics, and there is increasing use of small-bowel and colonic transit measurements in clinical practice as well. The main methods that are applied in clinical practice are substrate-hydrogen breath tests for small-bowel transit and radiopaque markers for colonic transit. Over the past 2-3 decades, scintigraphy has become the preferred standard in research studies, particularly for studies of pathophysiology and pharmacodynamics. New approaches include experimental stable isotope measurement of orocecal transit and the recently approved method using a wireless motility capsule that is validated as an accurate measurement of small-bowel and colonic transit.

AB - Transit assessment of the small intestine and colon is relevant in the study of physiology, pathophysiology, and pharmacodynamics, and there is increasing use of small-bowel and colonic transit measurements in clinical practice as well. The main methods that are applied in clinical practice are substrate-hydrogen breath tests for small-bowel transit and radiopaque markers for colonic transit. Over the past 2-3 decades, scintigraphy has become the preferred standard in research studies, particularly for studies of pathophysiology and pharmacodynamics. New approaches include experimental stable isotope measurement of orocecal transit and the recently approved method using a wireless motility capsule that is validated as an accurate measurement of small-bowel and colonic transit.

UR - http://www.scopus.com/inward/record.url?scp=84856408524&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84856408524&partnerID=8YFLogxK

U2 - 10.1053/j.semnuclmed.2011.10.004

DO - 10.1053/j.semnuclmed.2011.10.004

M3 - Article

C2 - 22293166

AN - SCOPUS:84856408524

VL - 42

SP - 113

EP - 123

JO - Seminars in Nuclear Medicine

JF - Seminars in Nuclear Medicine

SN - 0001-2998

IS - 2

ER -