Metastatic non-small cell lung carcinoma with involvement of extremity musculature: Case report and review of the literature

Gautam Ramakrishna, Gordon F. Harms, Charles Erlichman

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Hematogenous dissemination of non-small cell lung carcinoma (NSCLC) metastatic to skeletal musculature in the absence of osseous involvement is an infrequent occurrence. We retrospectively reviewed our institution's indexed database for patients evaluated from 1975 through 1997 who were diagnosed as having skeletal musculature metastases from NSCLC. Eight men and 2 women were identified (age range, 51-80 years at time of metastases). Four primary adenocarcinomas, 4 primary lung squamous cell carcinomas (SCCs), and 2 poorly differentiated primary NSCLCs were identified. Approximate tumor sizes ranged from 10 cm3 to 288 cm3. External-beam radia tion therapy was used in 7 of 10 cases; complete surgical excision was performed in 3 cases. Patients with known neoplasm who have extremity pain and negative findings on bone scan should be evaluated for soft tissue tumor involvement because such findings significantly affect clinical management. One case of lung SCC metastatic to the quadratus femoris muscle in a 63-year-old man is discussed in detail.

Original languageEnglish (US)
Pages (from-to)1333-1337
Number of pages5
JournalMayo Clinic proceedings
Volume75
Issue number12
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Medicine(all)

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