Metabolism as a guiding force for immunity

Jonathan Jung, Hu Zeng, Tiffany Horng

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Recent studies indicate that cellular metabolism plays a key role in supporting immune cell maintenance and development. Here, we review how metabolism guides immune cell activation and differentiation to distinct cellular states, and how differential regulation of metabolism allows for context-dependent support during activation and lineage commitment. We discuss emerging principles of metabolic support of immune cell function in physiology and disease, as well as their general relevance to the field of cell biology.

Original languageEnglish (US)
Pages (from-to)85-93
Number of pages9
JournalNature Cell Biology
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2019

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Immunity
Cell Biology
Cell Differentiation
Maintenance

ASJC Scopus subject areas

  • Cell Biology

Cite this

Metabolism as a guiding force for immunity. / Jung, Jonathan; Zeng, Hu; Horng, Tiffany.

In: Nature Cell Biology, Vol. 21, No. 1, 01.01.2019, p. 85-93.

Research output: Contribution to journalReview article

Jung, Jonathan ; Zeng, Hu ; Horng, Tiffany. / Metabolism as a guiding force for immunity. In: Nature Cell Biology. 2019 ; Vol. 21, No. 1. pp. 85-93.
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