Mechanisms in neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage

Vivien H. Lee, Jae Kuen Oh, Sharon L. Mulvagh, Eelco F M Wijdicks

Research output: Contribution to journalArticle

155 Citations (Scopus)

Abstract

Cardiac dysfunction after aneurysmal subarachnoid hemorrhage (SAH) is often referred to as "neurogenic stunned myocardium," which does not accurately reflect the suspected pathophysiology. We propose an alternative terminology, "neurogenic stress cardiomyopathy," as a more appropriate label based on our review of the current literature. This article will review the distinctive characteristics of SAH-induced cardiac dysfunction, hypotheses to explain the pathophysiology, and the supporting clinical and animal studies. Recognition of the unique features associated with SAH-induced cardiac complications allows optimal management of patients with SAH. We will also discuss the clinical and theoretical overlap of SAH-induced cardiac dysfunction with a syndrome known as tako-tsubo cardiomyopathy and explore therapeutic opportunities.

Original languageEnglish (US)
Pages (from-to)243-249
Number of pages7
JournalNeurocritical Care
Volume5
Issue number3
DOIs
StatePublished - Dec 2006

Fingerprint

Takotsubo Cardiomyopathy
Subarachnoid Hemorrhage
Myocardial Stunning
Terminology

Keywords

  • Cardiac apical ballooning
  • Neurogenic stunned myocardium
  • Subarachnoid hemorrhage
  • Tako-tsubo cardiomyopathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Critical Care and Intensive Care Medicine

Cite this

Mechanisms in neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage. / Lee, Vivien H.; Oh, Jae Kuen; Mulvagh, Sharon L.; Wijdicks, Eelco F M.

In: Neurocritical Care, Vol. 5, No. 3, 12.2006, p. 243-249.

Research output: Contribution to journalArticle

Lee, Vivien H. ; Oh, Jae Kuen ; Mulvagh, Sharon L. ; Wijdicks, Eelco F M. / Mechanisms in neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage. In: Neurocritical Care. 2006 ; Vol. 5, No. 3. pp. 243-249.
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