Matrix-assisted laser desorption ionization-time of flight mass spectrometry in clinical microbiology

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Despite widespread application of nucleic acid diagnostics, cultures remain integral in modern laboratories. Because cultures detect a large number of organism types, it is unlikely that they will disappear from clinical practice in the near future. Their downside is slow turn-around time, impacted by time to growth and identification of that growth. The latter is expedited using a new proteomic technology, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).

Original languageEnglish (US)
Pages (from-to)564-572
Number of pages9
JournalClinical Infectious Diseases
Volume57
Issue number4
DOIs
StatePublished - Aug 15 2013

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Microbiology
Mass Spectrometry
Lasers
Growth
Proteomics
Nucleic Acids
Technology

Keywords

  • Bacteria
  • Fungi
  • MALDI-TOF
  • Mass spectrometry
  • Matrix-assisted laser desorption ionization-time of flight

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

Matrix-assisted laser desorption ionization-time of flight mass spectrometry in clinical microbiology. / Patel, Robin.

In: Clinical Infectious Diseases, Vol. 57, No. 4, 15.08.2013, p. 564-572.

Research output: Contribution to journalArticle

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