Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries

Physics & Astronomy

• sequencing 100%
• inhibitors 85%
• selectivity 69%
• screening 63%
• proteins 58%
• protease 54%
• trypsin 53%
• affinity 20%
• platforms 15%
• interactions 14%
• probes 10%

Medicine & Life Sciences

• Amyloid beta-Protein Precursor 85%
• High-Throughput Nucleotide Sequencing 70%
• Trypsin Inhibitors 50%
• Kallikreins 46%
• Serine Proteases 41%
• Trypsin 37%
• Computer Simulation 34%
• Carrier Proteins 31%
• Peptide Hydrolases 30%
• Proteins 27%
• Therapeutics 6%

Chemical Compounds

• Combinatorial Library 89%
• Protein 30%
• Trypsin Inhibitor 22%
• Trypsin 17%
• Serine 17%
• Probe 11%