@article{1b61bb38010c4b62ba45aee7614882f5,
title = "Managing Chronic Cough as a Symptom in Children and Management Algorithms: CHEST Guideline and Expert Panel Report",
abstract = "Background: Cough is one of the most common presenting symptoms to general practitioners. The objective of this article is to collate the pediatric components of the CHEST chronic cough guidelines that have recently updated the 2006 guidelines to assist general and specialist medical practitioners in the evaluation and management of children who present with chronic cough. Methods: We reviewed all current CHEST Expert Cough Panel's statements and extracted recommendations and suggestions relating to children aged ≤ 14 years with chronic cough (> 4 weeks duration). Additionally, we undertook systematic reviews to update other sections we considered relevant and important. Results: The eight recent CHEST guidelines relevant to children, based on systematic reviews, reported some high-quality evidence in the management of chronic cough in children (eg, use of algorithms and management of wet/productive cough using appropriate antibiotics). However, much evidence is still inadequate, particularly in the management of non-specific cough in the community. Conclusions: The recommendations and suggestions related to the management of chronic cough in the pediatric age group have been based upon high-quality systematic reviews and are summarized in this article. Compared to the 2006 Cough Guidelines, there is now high-quality evidence for some aspects of the management of chronic cough in children. However, further studies particularly in primary health care are required.",
keywords = "children, cough, evidence-based medicine, guideline, treatment",
author = "Chang, {Anne B.} and Oppenheimer, {John J.} and Irwin, {Richard S.} and Adams, {Todd M.} and Altman, {Kenneth W.} and Elie Azoulay and Fiona Blackhall and Birring, {Surinder S.} and Bolser, {Donald C.} and Boulet, {Louis Philippe} and Braman, {Sidney S.} and Christopher Brightling and Priscilla Callahan-Lyon and Terrie Cowley and Paul Davenport and {El Solh}, {Ali A.} and Patricio Escalante and Field, {Stephen K.} and Dina Fisher and French, {Cynthia T.} and Cameron Grant and Harding, {Susan M.} and Anthony Harnden and Hill, {Adam T.} and Kahrilas, {Peter J.} and Joanne Kavanagh and Keogh, {Karina A.} and Kefang Lai and Lane, {Andrew P.} and Craig Lilly and Kaiser Lim and Mark Lown and Madison, {J. Mark} and Malesker, {Mark A.} and Stuart Mazzone and Lorcan McGarvey and Alex Molasoitis and Murad, {M. Hassan} and Mangala Narasimhan and John Oppenheimer and Russell, {Richard J.} and Ryu, {Jay H.} and Sonal Singh and Smith, {Maeve P.} and Tarlo, {Susan M.} and Vertigan, {Anne E.}",
note = "Funding Information: Financial/nonfinancial disclosures: The authors have reported to CHEST the following: A. B. C. is an author and reviewer UpToDate; data safety monitoring board member for a vaccine study (Glaxo); advisor for study design of an unlicensed product (Merck); has also received multiple peer-reviewed competitive grants [1154302, 1170958, 1042601] from the Australian National Health and Medical Research Council (NHMRC). No financial conflicts of interest regarding the content of this manuscript. A. B. C. is supported by an NHMRC practitioner fellowship [grant 1154302] and holds multiple grants awarded from the NHMRC related to diseases associated with pediatric cough. J. J. O. reports the following: American Board of Allergy and Immunology, Board of Directors; Annals of Allergy and Allergy Watch, Associate Editor; UpToDate, reviewer; Clinical Research, AstraZeneca, Boehringer Ingelheim, Glaxo, Medimmune, and Novartis; Adjudication Committee, AstraZeneca and Novartis; data safety monitoring board, The Ohio State University; and consultant, Glaxo, Myelin, Church and Dwight, and Meda. R. S. I. has no financial or intellectual conflicts of interest regarding the content of this manuscript. Moreover, while RSI was the Editor in Chief of CHEST, the review and all editorial decisions regarding this manuscript were independently made by others. ",
year = "2020",
month = jul,
doi = "10.1016/j.chest.2020.01.042",
language = "English (US)",
volume = "158",
pages = "303--329",
journal = "Chest",
issn = "0012-3692",
publisher = "American College of Chest Physicians",
number = "1",
}