Magnetic resonance elastography of the lungs

Kiaran Patrick McGee, Yogesh Mariappan, Rolf D. Hubmayr, Anthony Romano, Armando Manduca, Richard Lorne Ehman

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.

Original languageEnglish (US)
Title of host publicationMagnetic Resonance Elastography
PublisherSpringer New York
Pages99-108
Number of pages10
Volume9781493915750
ISBN (Print)9781493915750, 1493915746, 9781493915743
DOIs
StatePublished - Jul 1 2014

Fingerprint

Elasticity Imaging Techniques
Lung
Magnetic Resonance Spectroscopy
Lung Diseases
Noise

ASJC Scopus subject areas

  • Medicine(all)

Cite this

McGee, K. P., Mariappan, Y., Hubmayr, R. D., Romano, A., Manduca, A., & Ehman, R. L. (2014). Magnetic resonance elastography of the lungs. In Magnetic Resonance Elastography (Vol. 9781493915750, pp. 99-108). Springer New York. https://doi.org/10.1007/978-1-4939-1575-0_9

Magnetic resonance elastography of the lungs. / McGee, Kiaran Patrick; Mariappan, Yogesh; Hubmayr, Rolf D.; Romano, Anthony; Manduca, Armando; Ehman, Richard Lorne.

Magnetic Resonance Elastography. Vol. 9781493915750 Springer New York, 2014. p. 99-108.

Research output: Chapter in Book/Report/Conference proceedingChapter

McGee, KP, Mariappan, Y, Hubmayr, RD, Romano, A, Manduca, A & Ehman, RL 2014, Magnetic resonance elastography of the lungs. in Magnetic Resonance Elastography. vol. 9781493915750, Springer New York, pp. 99-108. https://doi.org/10.1007/978-1-4939-1575-0_9
McGee KP, Mariappan Y, Hubmayr RD, Romano A, Manduca A, Ehman RL. Magnetic resonance elastography of the lungs. In Magnetic Resonance Elastography. Vol. 9781493915750. Springer New York. 2014. p. 99-108 https://doi.org/10.1007/978-1-4939-1575-0_9
McGee, Kiaran Patrick ; Mariappan, Yogesh ; Hubmayr, Rolf D. ; Romano, Anthony ; Manduca, Armando ; Ehman, Richard Lorne. / Magnetic resonance elastography of the lungs. Magnetic Resonance Elastography. Vol. 9781493915750 Springer New York, 2014. pp. 99-108
@inbook{5a690292996c439389b10f8a4b7ef491,
title = "Magnetic resonance elastography of the lungs",
abstract = "The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.",
author = "McGee, {Kiaran Patrick} and Yogesh Mariappan and Hubmayr, {Rolf D.} and Anthony Romano and Armando Manduca and Ehman, {Richard Lorne}",
year = "2014",
month = "7",
day = "1",
doi = "10.1007/978-1-4939-1575-0_9",
language = "English (US)",
isbn = "9781493915750",
volume = "9781493915750",
pages = "99--108",
booktitle = "Magnetic Resonance Elastography",
publisher = "Springer New York",

}

TY - CHAP

T1 - Magnetic resonance elastography of the lungs

AU - McGee, Kiaran Patrick

AU - Mariappan, Yogesh

AU - Hubmayr, Rolf D.

AU - Romano, Anthony

AU - Manduca, Armando

AU - Ehman, Richard Lorne

PY - 2014/7/1

Y1 - 2014/7/1

N2 - The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.

AB - The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.

UR - http://www.scopus.com/inward/record.url?scp=84929860596&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929860596&partnerID=8YFLogxK

U2 - 10.1007/978-1-4939-1575-0_9

DO - 10.1007/978-1-4939-1575-0_9

M3 - Chapter

AN - SCOPUS:84929860596

SN - 9781493915750

SN - 1493915746

SN - 9781493915743

VL - 9781493915750

SP - 99

EP - 108

BT - Magnetic Resonance Elastography

PB - Springer New York

ER -