Magnetic resonance elastography of the lungs

Kiaran Patrick McGee, Yogesh Mariappan, Rolf D. Hubmayr, Anthony Romano, Armando Manduca, Richard Lorne Ehman

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.

Original languageEnglish (US)
Title of host publicationMagnetic Resonance Elastography
PublisherSpringer New York
Pages99-108
Number of pages10
Volume9781493915750
ISBN (Print)9781493915750, 1493915746, 9781493915743
DOIs
StatePublished - Jul 1 2014

ASJC Scopus subject areas

  • Medicine(all)

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    McGee, K. P., Mariappan, Y., Hubmayr, R. D., Romano, A., Manduca, A., & Ehman, R. L. (2014). Magnetic resonance elastography of the lungs. In Magnetic Resonance Elastography (Vol. 9781493915750, pp. 99-108). Springer New York. https://doi.org/10.1007/978-1-4939-1575-0_9