Abstract
The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.
| Original language | English (US) |
|---|---|
| Title of host publication | Magnetic Resonance Elastography |
| Publisher | Springer New York |
| Pages | 99-108 |
| Number of pages | 10 |
| Volume | 9781493915750 |
| ISBN (Print) | 9781493915750, 1493915746, 9781493915743 |
| DOIs | |
| State | Published - Jul 1 2014 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Magnetic resonance elastography of the lungs. / McGee, Kiaran Patrick; Mariappan, Yogesh; Hubmayr, Rolf D.; Romano, Anthony; Manduca, Armando; Ehman, Richard Lorne.
Magnetic Resonance Elastography. Vol. 9781493915750 Springer New York, 2014. p. 99-108.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Magnetic resonance elastography of the lungs
AU - McGee, Kiaran Patrick
AU - Mariappan, Yogesh
AU - Hubmayr, Rolf D.
AU - Romano, Anthony
AU - Manduca, Armando
AU - Ehman, Richard Lorne
PY - 2014/7/1
Y1 - 2014/7/1
N2 - The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.
AB - The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.
UR - http://www.scopus.com/inward/record.url?scp=84929860596&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929860596&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-1575-0_9
DO - 10.1007/978-1-4939-1575-0_9
M3 - Chapter
AN - SCOPUS:84929860596
SN - 9781493915750
SN - 1493915746
SN - 9781493915743
VL - 9781493915750
SP - 99
EP - 108
BT - Magnetic Resonance Elastography
PB - Springer New York
ER -