Long-term psychosocial outcome in typical absence epilepsy: Sometimes a wolf in sheeps' clothing

Elaine C Wirrell, Carol S. Camfield, Peter R. Camfield, Joseph M. Dooley, Kevin E. Gordon, Bruce Smith

Research output: Contribution to journalArticle

156 Citations (Scopus)

Abstract

Objectives: To determine whether young adults in whom typical absence epilepsy has been diagnosed in childhood have greater psychosocial difficulties than those with a nonneurologic chronic disease and to decide which seizure-related factors predict poor psychosocial outcome. Design: Population-based, inception cohort study. Setting: The only tertiary care pediatric hospital in the province of Nova Scotia. Patients: All children in whom typical absence epilepsy or juvenile rheumatoid arthritis (JRA) was diagnosed between January 1, 1977, and December 31, 1985, who were aged 18 years or older at follow-up in March 1994 to April 1995. Patients with typical absence epilepsy were identified from centralized electroencephalographic records for Nova Scotia, and those with JRA were identified from discharge diagnoses front the only children's hospital in Nova Scotia. Main Outcome Measure: Patients participated in a structured interview that assessed psychosocial function. Results: Fifty-six (86%) of the 65 patients with absence epilepsy and 61 (80%) of the 70 patients with JRA participated in the interview. The mean age of the patients at the interview was 23 years. Terminal remission occurred in 32 (57%) of the patients with typical absence epilepsy but in only 17 (28%) of the patients with JRA. Factor analysis identified 5 categories of outcome: academic- personal, behavioral, employment-financial, family relations, and social- personal relations. Patients with typical absence epilepsy had greater difficulties in the academic-personal and in the behavioral categories (P<.001) than those with JRA. Those with ongoing seizures had the least favorable outcome. Most seizure-related factors showed minimal correlation with psychosocial functioning. Conclusion: Young adults with a history of typical absence epilepsy, particularly those without remission of their seizures, often have poor psychosocial outcomes, considerably worse than those with JRA.

Original languageEnglish (US)
Pages (from-to)152-158
Number of pages7
JournalArchives of Pediatrics and Adolescent Medicine
Volume151
Issue number2
StatePublished - 1997
Externally publishedYes

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Absence Epilepsy
Clothing
Juvenile Arthritis
Nova Scotia
Seizures
Interviews
Young Adult
Pediatric Hospitals
Family Relations
Only Child
Tertiary Healthcare
Statistical Factor Analysis
Chronic Disease
Cohort Studies
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Wirrell, E. C., Camfield, C. S., Camfield, P. R., Dooley, J. M., Gordon, K. E., & Smith, B. (1997). Long-term psychosocial outcome in typical absence epilepsy: Sometimes a wolf in sheeps' clothing. Archives of Pediatrics and Adolescent Medicine, 151(2), 152-158.

Long-term psychosocial outcome in typical absence epilepsy : Sometimes a wolf in sheeps' clothing. / Wirrell, Elaine C; Camfield, Carol S.; Camfield, Peter R.; Dooley, Joseph M.; Gordon, Kevin E.; Smith, Bruce.

In: Archives of Pediatrics and Adolescent Medicine, Vol. 151, No. 2, 1997, p. 152-158.

Research output: Contribution to journalArticle

Wirrell, EC, Camfield, CS, Camfield, PR, Dooley, JM, Gordon, KE & Smith, B 1997, 'Long-term psychosocial outcome in typical absence epilepsy: Sometimes a wolf in sheeps' clothing', Archives of Pediatrics and Adolescent Medicine, vol. 151, no. 2, pp. 152-158.
Wirrell, Elaine C ; Camfield, Carol S. ; Camfield, Peter R. ; Dooley, Joseph M. ; Gordon, Kevin E. ; Smith, Bruce. / Long-term psychosocial outcome in typical absence epilepsy : Sometimes a wolf in sheeps' clothing. In: Archives of Pediatrics and Adolescent Medicine. 1997 ; Vol. 151, No. 2. pp. 152-158.
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