Lipodermatosclerosis: Review of cases evaluated at Mayo Clinic

Alison Bruce, Daniel D. Bennett, Christine M. Lohse, Thom W Rooke, Mark D P Davis

Research output: Contribution to journalReview article

53 Citations (Scopus)

Abstract

Background: Lipodermatosclerosis describes bound-down, sclerotic skin involving the lower extremities. Objective: Our purpose was to describe the demographic and clinical features of patients with lipodermatosclerosis. Methods: This was a retrospective study of patients presenting to Mayo Clinic between 1976 and 1998 with a diagnosis of lipodermatosclerosis. Results: Of 97 patients, 84 (87%) were women. Mean age was 62 years (range, 25-88 years). Mean body mass index was 34.3 (range, 17.8-71.5). Clinical signs were bilateral involvement in 44 patients (45%), induration localized to a discrete plaque in 49 (51%), erythema in 69 (71%), hyperpigmentation in 57 (59%), ulceration in 13 (13%), concomitant edema in 69 (71%), and varicosities in 55 (57%). Vascular studies performed on 72 patients showed abnormalities in 49: deep venous incompetence in 33 (67%), calf muscle pump abnormality in 19 (39%), abnormal pulsatility in 10 (20%), and obstruction in 1 (2%). Conclusion: Lipodermatosclerosis was associated with female sex, middle age, high body mass index, and venous abnormalities.

Original languageEnglish (US)
Pages (from-to)187-192
Number of pages6
JournalJournal of the American Academy of Dermatology
Volume46
Issue number2
DOIs
StatePublished - 2002

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Body Mass Index
Hyperpigmentation
Erythema
Blood Vessels
Lower Extremity
Edema
Retrospective Studies
Demography
Lipodermatosclerosis
Muscles
Skin

ASJC Scopus subject areas

  • Dermatology

Cite this

Lipodermatosclerosis : Review of cases evaluated at Mayo Clinic. / Bruce, Alison; Bennett, Daniel D.; Lohse, Christine M.; Rooke, Thom W; Davis, Mark D P.

In: Journal of the American Academy of Dermatology, Vol. 46, No. 2, 2002, p. 187-192.

Research output: Contribution to journalReview article

Bruce, Alison ; Bennett, Daniel D. ; Lohse, Christine M. ; Rooke, Thom W ; Davis, Mark D P. / Lipodermatosclerosis : Review of cases evaluated at Mayo Clinic. In: Journal of the American Academy of Dermatology. 2002 ; Vol. 46, No. 2. pp. 187-192.
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