Life-years gained resulting from screening colonoscopy compared with follow-up colonoscopy after a positive stool-based colorectal screening test

A. Mark Fendrick, Bijan J. Borah, A. Burak Ozbay, Leila Saoud, Paul J. Limburg

Research output: Contribution to journalArticlepeer-review

Abstract

Screening colonoscopies for colorectal cancer (CRC) are typically covered without patient cost-sharing, whereas follow-up colonoscopies for positive stool-based screening tests often incur patient costs. The objective of this analysis was to estimate and compare the life-years gained (LYG) per average-risk screening colonoscopy and follow-up colonoscopy after a positive stool-based test to better inform CRC coverage policy and reimbursement decisions. CRC outcomes from screening and follow-up colonoscopies versus no screening were estimated using CRC-AIM in a simulated population of average-risk individuals screened between ages 45–75 years. The LYG/colonoscopy per 1000 individuals was 0.09 for screening colonoscopy and 0.29 for follow-up colonoscopy. 0.01 and 0.04 CRC cases and 0.01 and 0.02 CRC deaths were averted per screening and follow-up colonoscopies, respectively. Coverage policies should be revised to encourage individuals to complete recommended screening processes.

Original languageEnglish (US)
Article number101701
JournalPreventive Medicine Reports
Volume26
DOIs
StatePublished - Apr 2022

Keywords

  • Adenoma
  • Colonoscopy
  • Colorectal cancer
  • Life-years gained
  • Screening
  • Simulation model
  • Stool-based test

ASJC Scopus subject areas

  • Health Informatics
  • Public Health, Environmental and Occupational Health

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