TY - JOUR
T1 - Leveraging epidemiology and clinical studies of cancer outcomes
T2 - Recommendations and opportunities for translational research
AU - Elena, Joanne W.
AU - Travis, Lois B.
AU - Simonds, Naoko I.
AU - Ambrosone, Christine B.
AU - Ballard-Barbash, Rachel
AU - Bhatia, Smita
AU - Cerhan, James R.
AU - Hartge, Patricia
AU - Heist, Rebecca S.
AU - Kushi, Lawrence H.
AU - Lash, Timothy L.
AU - Morton, Lindsay M.
AU - Onel, Kenan
AU - Pierce, John P.
AU - Robison, Leslie L.
AU - Rowland, Julia H.
AU - Schrag, Deborah
AU - Sellers, Thomas A.
AU - Seminara, Daniela
AU - Shu, Xiao Ou
AU - Thomas, Nancy E.
AU - Ulrich, Cornelia M.
AU - Freedman, Andrew N.
PY - 2013/1/16
Y1 - 2013/1/16
N2 - As the number of cancer survivors continues to grow, research investigating the factors that affect cancer outcomes, such as disease recurrence, risk of second malignant neoplasms, and the late effects of cancer treatments, becomes ever more important. Numerous epidemiologic studies have investigated factors that affect cancer risk, but far fewer have addressed the extent to which demographic, lifestyle, genomic, clinical, and psychosocial factors influence cancer outcomes. To identify research priorities as well as resources and infrastructure needed to advance the field of cancer outcomes and survivorship research, the National Cancer Institute sponsored a workshop titled "Utilizing Data from Cancer Survivor Cohorts: Understanding the Current State of Knowledge and Developing Future Research Priorities" on November 3, 2011, in Washington, DC. This commentary highlights recent findings presented at the workshop, opportunities to leverage existing data, and recommendations for future research, data, and infrastructure needed to address high priority clinical and research questions. Multidisciplinary teams that include epidemiologists, clinicians, biostatisticians, and bioinformaticists will be essential to facilitate future cancer outcome studies focused on improving clinical care of cancer patients, identifying those at high risk of poor outcomes, and implementing effective interventions to ultimately improve the quality and duration of survival.
AB - As the number of cancer survivors continues to grow, research investigating the factors that affect cancer outcomes, such as disease recurrence, risk of second malignant neoplasms, and the late effects of cancer treatments, becomes ever more important. Numerous epidemiologic studies have investigated factors that affect cancer risk, but far fewer have addressed the extent to which demographic, lifestyle, genomic, clinical, and psychosocial factors influence cancer outcomes. To identify research priorities as well as resources and infrastructure needed to advance the field of cancer outcomes and survivorship research, the National Cancer Institute sponsored a workshop titled "Utilizing Data from Cancer Survivor Cohorts: Understanding the Current State of Knowledge and Developing Future Research Priorities" on November 3, 2011, in Washington, DC. This commentary highlights recent findings presented at the workshop, opportunities to leverage existing data, and recommendations for future research, data, and infrastructure needed to address high priority clinical and research questions. Multidisciplinary teams that include epidemiologists, clinicians, biostatisticians, and bioinformaticists will be essential to facilitate future cancer outcome studies focused on improving clinical care of cancer patients, identifying those at high risk of poor outcomes, and implementing effective interventions to ultimately improve the quality and duration of survival.
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U2 - 10.1093/jnci/djs473
DO - 10.1093/jnci/djs473
M3 - Review article
C2 - 23197494
AN - SCOPUS:84872518586
SN - 0027-8874
VL - 105
SP - 85
EP - 94
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 2
ER -