The hallmark of Cogan's syndrome is the presence of ocular inflammation and audiovestibular dysfunction. These findings may be accompanied by the evidence of a systemic vasculitis that involves large blood vessels. Interstitial keratitis is the most common form of ocular involvement. Audiovestibular dysfunction may lead to the acute onset of vertigo, tinnitus, nausea, and vomiting. Vasculitis in Cogan's syndrome may take the form of aortitis, renal artery stenosis, or occlusion of the great vessels.
|Original language||English (US)|
|Title of host publication||A Clinician's Pearls and Myths in Rheumatology|
|Number of pages||9|
|State||Published - Dec 1 2009|
ASJC Scopus subject areas