Left ventricular performance before and after aortocoronary artery bypass surgery

J. H. Chesebro, E. L. Ritman, R. L. Frye, H. C. Smith, R. E. Vlietstra, J. R. Pluth

Research output: Contribution to journalArticle

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Abstract

Left ventricular performance was studied before and late (mean 12-17 months) after aortocoronary artery bypass surgery by quantitative, computer-based videoangiography. We measured total function (left ventricular ejection fraction, volumes and end-diastolic pressure) at rest (in 60 patients) and before and after exercise (abnormal exercise hemodynamics preoperatively in 32 patients) and regional function (peak rate of systolic wall thickening) at rest (in 60 patients) and before and after administration of nitroglycerin (in 19 patients). Total left ventricular function at rest is usually unchanged postoperatively. Excercise hemodynamics are more sensitive indexes of performance and, if abnormal, usually improve postoperatively if revascularization has been complete and extensive myocardial infarction has not occurred. Regional myocardial function usually improves postoperatively if the bypass graft to the region is patent and has a blood flow of more than 60 ml/min (measured late postoperatively by videodensitometry) and if no previous infarction was present in the region. Myocardial infarction and graft blood flow of 40 ml/min or less are the two main factors that prevent improvement in abnormal regions defined by the regional wall thickening method when bypass grafts are patent. Regions supplied by occluded grafts show decreases in regional function. The preoperative wall-thickening response to administration of nitroglycerin can be used to distinguish ischemia and significant myocardial infarction and to predict the successful response to aortocoronary bypass graft surgery.

Original languageEnglish (US)
JournalCirculation
Volume65
Issue number7 II
StatePublished - 1982

Fingerprint

Coronary Artery Bypass
Arteries
Transplants
Myocardial Infarction
Nitroglycerin
Hemodynamics
Exercise
Left Ventricular Function
Stroke Volume
Infarction
Ischemia
Blood Pressure

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Chesebro, J. H., Ritman, E. L., Frye, R. L., Smith, H. C., Vlietstra, R. E., & Pluth, J. R. (1982). Left ventricular performance before and after aortocoronary artery bypass surgery. Circulation, 65(7 II).

Left ventricular performance before and after aortocoronary artery bypass surgery. / Chesebro, J. H.; Ritman, E. L.; Frye, R. L.; Smith, H. C.; Vlietstra, R. E.; Pluth, J. R.

In: Circulation, Vol. 65, No. 7 II, 1982.

Research output: Contribution to journalArticle

Chesebro, JH, Ritman, EL, Frye, RL, Smith, HC, Vlietstra, RE & Pluth, JR 1982, 'Left ventricular performance before and after aortocoronary artery bypass surgery', Circulation, vol. 65, no. 7 II.
Chesebro JH, Ritman EL, Frye RL, Smith HC, Vlietstra RE, Pluth JR. Left ventricular performance before and after aortocoronary artery bypass surgery. Circulation. 1982;65(7 II).
Chesebro, J. H. ; Ritman, E. L. ; Frye, R. L. ; Smith, H. C. ; Vlietstra, R. E. ; Pluth, J. R. / Left ventricular performance before and after aortocoronary artery bypass surgery. In: Circulation. 1982 ; Vol. 65, No. 7 II.
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