Left ventricular function in subacute and chronic mitral regurgitation. Effect on function early postoperatively

G. J. Kontos, H. V. Schaff, B. J. Gersh, A. A. Bove

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Quantitative analysis of biplane ventriculograms, including calculation of the end-systolic pressure/volume ratio, was used to define left ventricular systolic performance in 10 normal subjects, 10 patients with symptomatic subacute (< 6 months' duration) mitral regurgitation, and 18 patients with symptomatic chronic mitral regurgitation. Left ventricular volume, mass, and systolic function were similar for patients with subacute and with chronic mitral regurgitation, suggesting that some patients with recent-onset nonischemic mitral regurgitation have partial adaptation to chronic valve insufficiency prior to their symptomatic event. Rate of development of left ventricular wall stress in early systole was increased in subacute mitral regurgitation compared with chronic mitral regurgitation and normal subjects. Duration of symptoms did not correlate with degree of ventricular adaptation to mitral regurgitation, and end-systolic indices of left ventricular performance did not predict early postoperative clinical response to valve replacement or repair.

Original languageEnglish (US)
Pages (from-to)163-169
Number of pages7
JournalJournal of Thoracic and Cardiovascular Surgery
Volume98
Issue number2
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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