Left atrial appendage exclusion for atrial fibrillation

Faisal F. Syed, Christopher V. DeSimone, Paul Andrew Friedman, Samuel J Asirvatham

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Percutaneous left atrial appendage (LAA) closure is being increasingly used as a treatment strategy to prevent stroke in patients with atrial fibrillation (AF) who have contraindications to anticoagulants. Several approaches and devices have been developed in the last few years, each with their own unique set of advantages and disadvantages. In this article, the published studies on surgical and percutaneous approaches to LAA closure are reviewed, focusing on stroke mechanisms in AF, LAA structure and function relevant to stroke prevention, practical differences in procedural approach, and clinical considerations surrounding management.

Original languageEnglish (US)
Pages (from-to)601-625
Number of pages25
JournalCardiology Clinics
Volume32
Issue number4
DOIs
StatePublished - 2014

    Fingerprint

Keywords

  • Atrial fibrillation
  • Left atrial appendage
  • Percutaneous appendage closure
  • Stroke prevention

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this