KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival

Elena Vendramini; Riccardo Bomben; Federico Pozzo; Dania Benedetti; Tamara Bittolo; Francesca Maria Rossi; Michele Dal Bo; Kari G. Rabe; Gabriele Pozzato; Francesco Zaja; Annalisa Chiarenza; Francesco Di Raimondo; Esteban Braggio; Sameer A. Parikh; Neil E. Kay; Tait D. Shanafelt; Giovanni Del Poeta; Valter Gattei; Antonella Zucchetto

doi:10.1038/s41375-019-0444-6

KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival

Elena Vendramini, Riccardo Bomben, Federico Pozzo, Dania Benedetti, Tamara Bittolo, Francesca Maria Rossi, Michele Dal Bo, Kari G. Rabe, Gabriele Pozzato, Francesco Zaja, Annalisa Chiarenza, Francesco Di Raimondo, Esteban Braggio, Sameer A. Parikh, Neil E. Kay, Tait D. Shanafelt, Giovanni Del Poeta, Valter Gattei, Antonella Zucchetto

Research output: Contribution to journal › Letter › peer-review

6 Scopus citations

Original language	English (US)
Pages (from-to)	2111-2115
Number of pages	5
Journal	Leukemia
Volume	33
Issue number	8
DOIs	https://doi.org/10.1038/s41375-019-0444-6
State	Published - Aug 1 2019

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

Access to Document

10.1038/s41375-019-0444-6

Cite this

Vendramini, E., Bomben, R., Pozzo, F., Benedetti, D., Bittolo, T., Rossi, F. M., Dal Bo, M., Rabe, K. G., Pozzato, G., Zaja, F., Chiarenza, A., Di Raimondo, F., Braggio, E., Parikh, S. A., Kay, N. E., Shanafelt, T. D., Del Poeta, G., Gattei, V., & Zucchetto, A. (2019). KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival. Leukemia, 33(8), 2111-2115. https://doi.org/10.1038/s41375-019-0444-6

Vendramini, E, Bomben, R, Pozzo, F, Benedetti, D, Bittolo, T, Rossi, FM, Dal Bo, M, Rabe, KG, Pozzato, G, Zaja, F, Chiarenza, A, Di Raimondo, F, Braggio, E , Parikh, SA , Kay, NE, Shanafelt, TD, Del Poeta, G, Gattei, V & Zucchetto, A 2019, 'KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival', Leukemia, vol. 33, no. 8, pp. 2111-2115. https://doi.org/10.1038/s41375-019-0444-6

@article{935377cfc3b648ab93d7daaad7324771,

title = "KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival",

author = "Elena Vendramini and Riccardo Bomben and Federico Pozzo and Dania Benedetti and Tamara Bittolo and Rossi, {Francesca Maria} and {Dal Bo}, Michele and Rabe, {Kari G.} and Gabriele Pozzato and Francesco Zaja and Annalisa Chiarenza and {Di Raimondo}, Francesco and Esteban Braggio and Parikh, {Sameer A.} and Kay, {Neil E.} and Shanafelt, {Tait D.} and {Del Poeta}, Giovanni and Valter Gattei and Antonella Zucchetto",

note = "Funding Information: Acknowledgements The study was supported by the Fondazione Umberto Veronesi, Post-doctoral Fellowships-year 2018 (to EV); Associazione Italiana Ricerca Cancro (AIRC), Investigator Grant IG-21687; Progetto Giovani Ricercatori no. GR-2011-02346826, no. GR-2011-02347441, and no.GR-2011-02351370, Ministero della Salute, Rome, Italy; Progetto Ricerca Finalizzata PE 2016-02362756, Minis-tero della Salute, Rome, Italy; Associazione Italiana contro le Leuce-mie, linfomi e mielomi (AIL), Venezia Section, Pramaggiore Group, Italy; Linfo-check - Bando ricerca - contributo art. 15, comma 2, lett b) LR 17/2014; “5x1000 Intramural Program”, Centro di Riferimento Oncologico, Aviano, Italy; National Cancer Institute, CA197120 (to TDS and NEK). Authors wish to thank Gustavo Baldassarre (Division of Molecular Oncology, Department of Translational Research, CRO Aviano, Italy) for helpful discussion.",

year = "2019",

month = aug,

day = "1",

doi = "10.1038/s41375-019-0444-6",

language = "English (US)",

volume = "33",

pages = "2111--2115",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Nature Publishing Group",

number = "8",

}

TY - JOUR

T1 - KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival

AU - Vendramini, Elena

AU - Bomben, Riccardo

AU - Pozzo, Federico

AU - Benedetti, Dania

AU - Bittolo, Tamara

AU - Rossi, Francesca Maria

AU - Dal Bo, Michele

AU - Rabe, Kari G.

AU - Pozzato, Gabriele

AU - Zaja, Francesco

AU - Chiarenza, Annalisa

AU - Di Raimondo, Francesco

AU - Braggio, Esteban

AU - Parikh, Sameer A.

AU - Kay, Neil E.

AU - Shanafelt, Tait D.

AU - Del Poeta, Giovanni

AU - Gattei, Valter

AU - Zucchetto, Antonella

N1 - Funding Information: Acknowledgements The study was supported by the Fondazione Umberto Veronesi, Post-doctoral Fellowships-year 2018 (to EV); Associazione Italiana Ricerca Cancro (AIRC), Investigator Grant IG-21687; Progetto Giovani Ricercatori no. GR-2011-02346826, no. GR-2011-02347441, and no.GR-2011-02351370, Ministero della Salute, Rome, Italy; Progetto Ricerca Finalizzata PE 2016-02362756, Minis-tero della Salute, Rome, Italy; Associazione Italiana contro le Leuce-mie, linfomi e mielomi (AIL), Venezia Section, Pramaggiore Group, Italy; Linfo-check - Bando ricerca - contributo art. 15, comma 2, lett b) LR 17/2014; “5x1000 Intramural Program”, Centro di Riferimento Oncologico, Aviano, Italy; National Cancer Institute, CA197120 (to TDS and NEK). Authors wish to thank Gustavo Baldassarre (Division of Molecular Oncology, Department of Translational Research, CRO Aviano, Italy) for helpful discussion.

PY - 2019/8/1

Y1 - 2019/8/1

UR - http://www.scopus.com/inward/record.url?scp=85063040196&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063040196&partnerID=8YFLogxK

U2 - 10.1038/s41375-019-0444-6

DO - 10.1038/s41375-019-0444-6

M3 - Letter

C2 - 30872781

AN - SCOPUS:85063040196

SN - 0887-6924

VL - 33

SP - 2111

EP - 2115

JO - Leukemia

JF - Leukemia

IS - 8

ER -

KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this