Ketamine: Stimulating antidepressant treatment?

Gin S. Malhi, Yulisha Byrow, Frederick Cassidy, Andrea Cipriani, Koen Demyttenaere, Mark A Frye, Michael Gitlin, Sidney H. Kennedy, Terence A. Ketter, Raymond W. Lam, Rupert McShane, Alex J. Mitchell, Michael J. Ostacher, Sakina J. Rizvi, Michael E. Thase, Mauricio Tohen

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

The appeal of ketamine - in promptly ameliorating depressive symptoms even in those with non-response - has led to a dramatic increase in its off-label use. Initial promising results await robust corroboration and key questions remain, particularly concerning its long-term administration. It is, therefore, timely to review the opinions of mood disorder experts worldwide pertaining to ketamine's potential as an option for treating depression and provide a synthesis of perspectives - derived from evidence and clinical experience - and to consider strategies for future investigations.

Original languageEnglish (US)
Pages (from-to)E5-E9
JournalBJPsych Open
Volume2
Issue number3
DOIs
StatePublished - Jan 1 2016

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Ketamine
Antidepressive Agents
Depression
Off-Label Use
Mood Disorders
Therapeutics

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Malhi, G. S., Byrow, Y., Cassidy, F., Cipriani, A., Demyttenaere, K., Frye, M. A., ... Tohen, M. (2016). Ketamine: Stimulating antidepressant treatment? BJPsych Open, 2(3), E5-E9. https://doi.org/10.1192/bjpo.bp.116.002923

Ketamine : Stimulating antidepressant treatment? / Malhi, Gin S.; Byrow, Yulisha; Cassidy, Frederick; Cipriani, Andrea; Demyttenaere, Koen; Frye, Mark A; Gitlin, Michael; Kennedy, Sidney H.; Ketter, Terence A.; Lam, Raymond W.; McShane, Rupert; Mitchell, Alex J.; Ostacher, Michael J.; Rizvi, Sakina J.; Thase, Michael E.; Tohen, Mauricio.

In: BJPsych Open, Vol. 2, No. 3, 01.01.2016, p. E5-E9.

Research output: Contribution to journalReview article

Malhi, GS, Byrow, Y, Cassidy, F, Cipriani, A, Demyttenaere, K, Frye, MA, Gitlin, M, Kennedy, SH, Ketter, TA, Lam, RW, McShane, R, Mitchell, AJ, Ostacher, MJ, Rizvi, SJ, Thase, ME & Tohen, M 2016, 'Ketamine: Stimulating antidepressant treatment?', BJPsych Open, vol. 2, no. 3, pp. E5-E9. https://doi.org/10.1192/bjpo.bp.116.002923
Malhi GS, Byrow Y, Cassidy F, Cipriani A, Demyttenaere K, Frye MA et al. Ketamine: Stimulating antidepressant treatment? BJPsych Open. 2016 Jan 1;2(3):E5-E9. https://doi.org/10.1192/bjpo.bp.116.002923
Malhi, Gin S. ; Byrow, Yulisha ; Cassidy, Frederick ; Cipriani, Andrea ; Demyttenaere, Koen ; Frye, Mark A ; Gitlin, Michael ; Kennedy, Sidney H. ; Ketter, Terence A. ; Lam, Raymond W. ; McShane, Rupert ; Mitchell, Alex J. ; Ostacher, Michael J. ; Rizvi, Sakina J. ; Thase, Michael E. ; Tohen, Mauricio. / Ketamine : Stimulating antidepressant treatment?. In: BJPsych Open. 2016 ; Vol. 2, No. 3. pp. E5-E9.
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