KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD

Sandra J. Taler, Rajiv Agarwal, George L. Bakris, Joseph T. Flynn, Peter M. Nilsson, Mahboob Rahman, Paul W. Sanders, Stephen C. Textor, Matthew R. Weir, Raymond R. Townsend

Research output: Contribution to journalArticle

101 Scopus citations

Abstract

In response to the 2012 KDIGO (Kidney Disease: Improving Global Outcomes) guideline for blood pressure management in patients with chronic kidney disease not on dialysis, the National Kidney Foundation organized a group of US experts in hypertension and transplant nephrology to review the recommendations and comment on their relevancy in the context of current US clinical practice and concerns. The overriding message was the dearth of clinical trial evidence to provide strong evidence-based recommendations. For patients with CKD with normal to mildly increased albuminuria, goal blood pressure has been relaxed to ≤140/90 mm Hg for both diabetic and nondiabetic patients. In contrast, KDIGO continues to recommend goal blood pressure ≤130/80 mm Hg for patients with chronic kidney disease with moderately or severely increased albuminuria and for all renal transplant recipients regardless of the presence of proteinuria, without supporting data. The expert panel thought the KDIGO recommendations were generally reasonable but lacking in sufficient evidence support and that additional studies are greatly needed.

Original languageEnglish (US)
Pages (from-to)201-213
Number of pages13
JournalAmerican Journal of Kidney Diseases
Volume62
Issue number2
DOIs
StatePublished - Aug 2013

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Keywords

  • Kidney Disease: Improving Global Outcomes (KDIGO)
  • blood pressure
  • guideline

ASJC Scopus subject areas

  • Nephrology

Cite this

Taler, S. J., Agarwal, R., Bakris, G. L., Flynn, J. T., Nilsson, P. M., Rahman, M., Sanders, P. W., Textor, S. C., Weir, M. R., & Townsend, R. R. (2013). KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD. American Journal of Kidney Diseases, 62(2), 201-213. https://doi.org/10.1053/j.ajkd.2013.03.018