Isolated angiitis of the CNS presenting as subarachnoid haemorrhage

Rajeev Kumar, Eelco F M Wijdicks, Robert D Jr. Brown, Joseph E Parisi, Charlotte A. Hammond

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Isolated angiitis of the CNS (IACNS) commonly presents with recurrent ischaemic or haemorrhagic infarcts, but subarachnoid haemorrhage is rare. Three patients with IACNS and subarachnoid haemorrhage are reported. Florid granulomatous angiitis with Langhans and foreign body type giant cells was found at necropsy in a child with sudden death. In two other patients the diagnosis was made angiographically. In one patient multifocal infarcts on MRI became evident one week after subarachnoid haemorrhage despite initial treatment with prednisone. Subarachnoid haemorrhage may be the first presentation of IACNS. Characteristic radiographic findings may allow early diagnosis.

Original languageEnglish (US)
Pages (from-to)649-651
Number of pages3
JournalJournal of Neurology Neurosurgery and Psychiatry
Volume62
Issue number6
StatePublished - Jun 1997

Fingerprint

Subarachnoid Hemorrhage
Vasculitis
Foreign Body Giant Cells
Central Nervous System Vasculitis
Sudden Death
Prednisone
Early Diagnosis
Therapeutics

Keywords

  • Subarachnoid haemorrhage
  • Vasculitis

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health

Cite this

Kumar, R., Wijdicks, E. F. M., Brown, R. D. J., Parisi, J. E., & Hammond, C. A. (1997). Isolated angiitis of the CNS presenting as subarachnoid haemorrhage. Journal of Neurology Neurosurgery and Psychiatry, 62(6), 649-651.

Isolated angiitis of the CNS presenting as subarachnoid haemorrhage. / Kumar, Rajeev; Wijdicks, Eelco F M; Brown, Robert D Jr.; Parisi, Joseph E; Hammond, Charlotte A.

In: Journal of Neurology Neurosurgery and Psychiatry, Vol. 62, No. 6, 06.1997, p. 649-651.

Research output: Contribution to journalArticle

Kumar, R, Wijdicks, EFM, Brown, RDJ, Parisi, JE & Hammond, CA 1997, 'Isolated angiitis of the CNS presenting as subarachnoid haemorrhage', Journal of Neurology Neurosurgery and Psychiatry, vol. 62, no. 6, pp. 649-651.
Kumar, Rajeev ; Wijdicks, Eelco F M ; Brown, Robert D Jr. ; Parisi, Joseph E ; Hammond, Charlotte A. / Isolated angiitis of the CNS presenting as subarachnoid haemorrhage. In: Journal of Neurology Neurosurgery and Psychiatry. 1997 ; Vol. 62, No. 6. pp. 649-651.
@article{d26635877a364798a9d93ae2bce23ca8,
title = "Isolated angiitis of the CNS presenting as subarachnoid haemorrhage",
abstract = "Isolated angiitis of the CNS (IACNS) commonly presents with recurrent ischaemic or haemorrhagic infarcts, but subarachnoid haemorrhage is rare. Three patients with IACNS and subarachnoid haemorrhage are reported. Florid granulomatous angiitis with Langhans and foreign body type giant cells was found at necropsy in a child with sudden death. In two other patients the diagnosis was made angiographically. In one patient multifocal infarcts on MRI became evident one week after subarachnoid haemorrhage despite initial treatment with prednisone. Subarachnoid haemorrhage may be the first presentation of IACNS. Characteristic radiographic findings may allow early diagnosis.",
keywords = "Subarachnoid haemorrhage, Vasculitis",
author = "Rajeev Kumar and Wijdicks, {Eelco F M} and Brown, {Robert D Jr.} and Parisi, {Joseph E} and Hammond, {Charlotte A.}",
year = "1997",
month = "6",
language = "English (US)",
volume = "62",
pages = "649--651",
journal = "Journal of Neurology, Neurosurgery and Psychiatry",
issn = "0022-3050",
publisher = "BMJ Publishing Group",
number = "6",

}

TY - JOUR

T1 - Isolated angiitis of the CNS presenting as subarachnoid haemorrhage

AU - Kumar, Rajeev

AU - Wijdicks, Eelco F M

AU - Brown, Robert D Jr.

AU - Parisi, Joseph E

AU - Hammond, Charlotte A.

PY - 1997/6

Y1 - 1997/6

N2 - Isolated angiitis of the CNS (IACNS) commonly presents with recurrent ischaemic or haemorrhagic infarcts, but subarachnoid haemorrhage is rare. Three patients with IACNS and subarachnoid haemorrhage are reported. Florid granulomatous angiitis with Langhans and foreign body type giant cells was found at necropsy in a child with sudden death. In two other patients the diagnosis was made angiographically. In one patient multifocal infarcts on MRI became evident one week after subarachnoid haemorrhage despite initial treatment with prednisone. Subarachnoid haemorrhage may be the first presentation of IACNS. Characteristic radiographic findings may allow early diagnosis.

AB - Isolated angiitis of the CNS (IACNS) commonly presents with recurrent ischaemic or haemorrhagic infarcts, but subarachnoid haemorrhage is rare. Three patients with IACNS and subarachnoid haemorrhage are reported. Florid granulomatous angiitis with Langhans and foreign body type giant cells was found at necropsy in a child with sudden death. In two other patients the diagnosis was made angiographically. In one patient multifocal infarcts on MRI became evident one week after subarachnoid haemorrhage despite initial treatment with prednisone. Subarachnoid haemorrhage may be the first presentation of IACNS. Characteristic radiographic findings may allow early diagnosis.

KW - Subarachnoid haemorrhage

KW - Vasculitis

UR - http://www.scopus.com/inward/record.url?scp=0030996741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030996741&partnerID=8YFLogxK

M3 - Article

VL - 62

SP - 649

EP - 651

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

SN - 0022-3050

IS - 6

ER -