Intraocular Pressure Spikes within First Postoperative Hours following Standard Trabeculectomy: Incidence and Associated Factors

Felipe Daher, Izabela Almeida, Michele Ushida, Bernardo Soares, Syril Dorairaj, Fabio N. Kanadani, Augusto Paranhos, Carolina P.B. Gracitelli, Tiago S. Prata

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the incidence of intraocular pressure (IOP) spikes within the first postoperative hours following trabeculectomy (TRAB) and to determine possible associated factors. Methods: An observational study was carried out. We enrolled consecutive patients undergoing standard TRAB with mitomycin C. They were examined twice within the first few postoperative hours (hours 1-2 and 4-6) and 3 times after TRAB (on days 1, 7, and 30). Demographic and ocular data were collected. Main outcome measurements were postoperative IOP values at each time point and the frequency of IOP spikes, defined as IOP ≥25 mm Hg. Results: A total of 40 eyes of 40 patients were included (mean age 59.62 ± 13.37 years). Although IOP was significantly reduced to 11.14 ± 7.99 mm Hg at hours 1-2 (p < 0.01) and to 11.52 ± 7.30 mm Hg at hours 4-6 (p < 0.01), IOP spikes were documented in 3 patients (7.5%). In the group of patients with IOP spikes, we noted that there was a high incidence of black patients and that the surgeries had been performed by fellow surgeons. Conclusion: Although the majority of the cases (92.5% of the patients) did not present IOP spikes, 7.5% of our patients presented the event. In selected cases, such as those with advanced disease, fixation threat, and of black race, IOP should be monitored during the first few postoperative hours for the identification and adequate management of potential IOP spikes, preventing undesirable outcomes.

Original languageEnglish (US)
Pages (from-to)142-147
Number of pages6
JournalOphthalmic Research
Volume59
Issue number3
DOIs
StatePublished - Apr 1 2018

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Trabeculectomy
Intraocular Pressure
Incidence
Mitomycin
Observational Studies
Demography

Keywords

  • Advanced glaucoma
  • Glaucoma surgery
  • Intraocular pressure spike
  • Trabeculectomy
  • Trabeculectomy adverse effects

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Intraocular Pressure Spikes within First Postoperative Hours following Standard Trabeculectomy : Incidence and Associated Factors. / Daher, Felipe; Almeida, Izabela; Ushida, Michele; Soares, Bernardo; Dorairaj, Syril; Kanadani, Fabio N.; Paranhos, Augusto; Gracitelli, Carolina P.B.; Prata, Tiago S.

In: Ophthalmic Research, Vol. 59, No. 3, 01.04.2018, p. 142-147.

Research output: Contribution to journalArticle

Daher, F, Almeida, I, Ushida, M, Soares, B, Dorairaj, S, Kanadani, FN, Paranhos, A, Gracitelli, CPB & Prata, TS 2018, 'Intraocular Pressure Spikes within First Postoperative Hours following Standard Trabeculectomy: Incidence and Associated Factors', Ophthalmic Research, vol. 59, no. 3, pp. 142-147. https://doi.org/10.1159/000480736
Daher, Felipe ; Almeida, Izabela ; Ushida, Michele ; Soares, Bernardo ; Dorairaj, Syril ; Kanadani, Fabio N. ; Paranhos, Augusto ; Gracitelli, Carolina P.B. ; Prata, Tiago S. / Intraocular Pressure Spikes within First Postoperative Hours following Standard Trabeculectomy : Incidence and Associated Factors. In: Ophthalmic Research. 2018 ; Vol. 59, No. 3. pp. 142-147.
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AU - Ushida, Michele

AU - Soares, Bernardo

AU - Dorairaj, Syril

AU - Kanadani, Fabio N.

AU - Paranhos, Augusto

AU - Gracitelli, Carolina P.B.

AU - Prata, Tiago S.

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N2 - Purpose: To evaluate the incidence of intraocular pressure (IOP) spikes within the first postoperative hours following trabeculectomy (TRAB) and to determine possible associated factors. Methods: An observational study was carried out. We enrolled consecutive patients undergoing standard TRAB with mitomycin C. They were examined twice within the first few postoperative hours (hours 1-2 and 4-6) and 3 times after TRAB (on days 1, 7, and 30). Demographic and ocular data were collected. Main outcome measurements were postoperative IOP values at each time point and the frequency of IOP spikes, defined as IOP ≥25 mm Hg. Results: A total of 40 eyes of 40 patients were included (mean age 59.62 ± 13.37 years). Although IOP was significantly reduced to 11.14 ± 7.99 mm Hg at hours 1-2 (p < 0.01) and to 11.52 ± 7.30 mm Hg at hours 4-6 (p < 0.01), IOP spikes were documented in 3 patients (7.5%). In the group of patients with IOP spikes, we noted that there was a high incidence of black patients and that the surgeries had been performed by fellow surgeons. Conclusion: Although the majority of the cases (92.5% of the patients) did not present IOP spikes, 7.5% of our patients presented the event. In selected cases, such as those with advanced disease, fixation threat, and of black race, IOP should be monitored during the first few postoperative hours for the identification and adequate management of potential IOP spikes, preventing undesirable outcomes.

AB - Purpose: To evaluate the incidence of intraocular pressure (IOP) spikes within the first postoperative hours following trabeculectomy (TRAB) and to determine possible associated factors. Methods: An observational study was carried out. We enrolled consecutive patients undergoing standard TRAB with mitomycin C. They were examined twice within the first few postoperative hours (hours 1-2 and 4-6) and 3 times after TRAB (on days 1, 7, and 30). Demographic and ocular data were collected. Main outcome measurements were postoperative IOP values at each time point and the frequency of IOP spikes, defined as IOP ≥25 mm Hg. Results: A total of 40 eyes of 40 patients were included (mean age 59.62 ± 13.37 years). Although IOP was significantly reduced to 11.14 ± 7.99 mm Hg at hours 1-2 (p < 0.01) and to 11.52 ± 7.30 mm Hg at hours 4-6 (p < 0.01), IOP spikes were documented in 3 patients (7.5%). In the group of patients with IOP spikes, we noted that there was a high incidence of black patients and that the surgeries had been performed by fellow surgeons. Conclusion: Although the majority of the cases (92.5% of the patients) did not present IOP spikes, 7.5% of our patients presented the event. In selected cases, such as those with advanced disease, fixation threat, and of black race, IOP should be monitored during the first few postoperative hours for the identification and adequate management of potential IOP spikes, preventing undesirable outcomes.

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