Intramembrane proton binding site linked to activation of bacterial pentameric ion channel

Medicine & Life Sciences

• Hydrogen Bonding 100%
• Protons 84%
• Ion Channels 82%
• Binding Sites 64%
• Mutation 37%
• Molecular Dynamics Simulation 37%
• Cysteine Loop Ligand-Gated Ion Channel Receptors 29%
• Electrophysiology 18%
• Histidine 18%
• Patch-Clamp Techniques 18%
• Mutagenesis 16%
• Oxygen 11%
• Kidney 8%
• Proteins 6%

Chemical Compounds

• Mutation 56%
• Proton 53%
• Hydrogen Bond 40%
• Ion 32%
• Molecular Dynamics 24%
• Simulation 20%
• Histidine 15%
• pH Value 13%
• Hydrogen 8%
• Crystal Structure 8%
• Dioxygen 8%
• Protein 6%
• Surface 5%