Intracranial cerebrovascular vasa vasorum associated with atherosclerosis and large thick-walled aneurysms

John L.D. Atkinson, Haruo Okazaki, Thoralf M. Sundt, Douglas A. Nichols, Daniel A. Rufenacht

Research output: Contribution to journalArticle

24 Scopus citations


Atherosclerotic plaques that develop in the extracranial circulation are usually extensively vascularized by vasa vasorum. However, human vasa vasorum associated with intracranial atherosclerosis has not been adequately addressed. Anterior and posterior circulation specimens from fresh autopsy material were studied under the magnification of a dissecting microscope and proliferative vasa vasorum was found to be frequently associated with intrinsic atheromatous plaques. Vasa vasorum associated with an incidental large aneurysm supports the radiological literature demonstrating that many large and giant thickwalled aneurysms exhibit vascularized walls on contrast computed tomography scans. This information may aid in the preoperative assessment and possible repair of these aneurysms.

Original languageEnglish (US)
Pages (from-to)365-369
Number of pages5
JournalSurgical Neurology
Issue number5
StatePublished - Nov 1991



  • Aneurysms
  • Cerebrovasculature
  • Human autopsy material
  • Microvasculature
  • Vasa vasorum

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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