Interpreting networks in systems biology

D. K. Arrell, A. Terzic

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Implementation of network systems biology principles offers unparalleled opportunity to synthesize and integrate inherently complex high-throughput data for meaningful interpretation. Nonstochastic network templates constructed from extant knowledge facilitate large data set prioritization and prognostication, identifying context-dependent candidates for follow-up functional validation and interpretation. In conjunction, enrichment and representation assessment refines comprehension of network-associated molecular functions and biological processes. Together, exploiting intrinsic network properties provides a value-added decision-support instrument for data deconvolution in systems biomedicine.

Original languageEnglish (US)
Pages (from-to)389-392
Number of pages4
JournalClinical pharmacology and therapeutics
Volume93
Issue number5
DOIs
StatePublished - May 1 2013

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Fingerprint Dive into the research topics of 'Interpreting networks in systems biology'. Together they form a unique fingerprint.

  • Cite this