Interpreting networks in systems biology

D. K. Arrell, Andre Terzic

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Implementation of network systems biology principles offers unparalleled opportunity to synthesize and integrate inherently complex high-throughput data for meaningful interpretation. Nonstochastic network templates constructed from extant knowledge facilitate large data set prioritization and prognostication, identifying context-dependent candidates for follow-up functional validation and interpretation. In conjunction, enrichment and representation assessment refines comprehension of network-associated molecular functions and biological processes. Together, exploiting intrinsic network properties provides a value-added decision-support instrument for data deconvolution in systems biomedicine.

Original languageEnglish (US)
Pages (from-to)389-392
Number of pages4
JournalClinical Pharmacology and Therapeutics
Volume93
Issue number5
DOIs
StatePublished - May 2013

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Biological Phenomena
Systems Biology
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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Interpreting networks in systems biology. / Arrell, D. K.; Terzic, Andre.

In: Clinical Pharmacology and Therapeutics, Vol. 93, No. 5, 05.2013, p. 389-392.

Research output: Contribution to journalArticle

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