Inositol hexaphosphate plus inositol induced complete remission in stage IV melanoma: A case report

Sharad Khurana, Candice Baldeo, Richard W. Joseph

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Inositol hexaphosphate (IP6) also called phytic acid is a polyphosphorylated carbohydrate naturally found in cereals, nuts, grains, and high-fiber-containing foods. It has been shown to inhibit the growth of many different tumor cell lines both in vitro and in vivo like colon, pancreas, liver, prostate, and even melanoma. Vitamin B inositol is a precursor of IP6 and another naturally occurring compound with anticancer properties. We present a case report of a patient with metastatic melanoma who declined traditional therapy and opted to try over the counter supplement IP6+inositol instead. To our surprise, the patient achieved a complete remission and remains in remission 3 years later. On the basis of this case and previous preclinical studies, we believe further research is indicated in exploring antiproliferative and potential immune stimulating effects of IP6+inositol in patients with metastatic melanoma.

Original languageEnglish (US)
Pages (from-to)322-324
Number of pages3
JournalMelanoma research
Volume29
Issue number3
DOIs
StatePublished - Jun 1 2019

Keywords

  • antitumor
  • inositol
  • inositol hexaphosphate
  • melanoma

ASJC Scopus subject areas

  • Oncology
  • Dermatology
  • Cancer Research

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