Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells

Medicine & Life Sciences

• Type 3 Cyclic Nucleotide Phosphodiesterases 100%
• Mesangial Cells 79%
• Cyclic Nucleotides 79%
• cilostamide 70%
• Isoenzymes 66%
• Phosphodiesterase Inhibitors 64%
• Mitogen-Activated Protein Kinases 52%
• Colforsin 43%
• Cilostazol 38%
• Type 4 Cyclic Nucleotide Phosphodiesterase 38%
• Rolipram 38%
• lixazinone 30%
• denbufylline 26%
• Epidermal Growth Factor 25%
• Thymidine 25%
• Protein Kinases 24%
• Cell Proliferation 17%
• Bucladesine 17%
• Cyclic AMP-Dependent Protein Kinases 13%
• Mitogens 13%
• Phosphorylation 9%